Evidence map›Paper›PMID 31547144›Full record

Trial reportInternational journal of molecular sciences2019

A Novel Prognostic DNA Methylation Panel for Colorectal Cancer.

Hsin-Hua Chung, Chih-Chi Kuo, Cheng-Wen Hsiao, Chao-Yang Chen, Je-Ming Hu, Chih-Hsiung Hsu, Yu-Ching Chou, Ya-Wen Lin, Yu-Lueng Shih

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Transcription factor expression repertoire basis for epigenetic and transcriptional subtypes of colorectal cancers.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Liquid biopsy in NSCLC: a new challenge in radiation therapy.Exploration of targeted anti-tumor therapy · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hsin-Hua ChungGraduate Institute of Medical Sciences, National Defense Medical Center, No. 161, Sec. 6, Minquan East Rd., Neihu District, Taipei 11490, Taiwan.ORCID 0000-0001-6872-3684
Chih-Chi KuoTeaching and Research Office, Tri-Service General Hospital Songshan Branch, No. 131, Jiankang Rd., Songshan District, Taipei 10581, Taiwan.
Cheng-Wen HsiaoDivision of Colorectal Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Chenggong Rd., Neihu District, Taipei 11490, Taiwan.
Chao-Yang ChenDivision of Colorectal Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Chenggong Rd., Neihu District, Taipei 11490, Taiwan.
Je-Ming HuGraduate Institute of Medical Sciences, National Defense Medical Center, No. 161, Sec. 6, Minquan East Rd., Neihu District, Taipei 11490, Taiwan.
Chih-Hsiung HsuGraduate Institute of Medical Sciences, National Defense Medical Center, No. 161, Sec. 6, Minquan East Rd., Neihu District, Taipei 11490, Taiwan.
Yu-Ching ChouSchool of Public Health, National Defense Medical Center, No. 161, Sec. 6, Minquan East Rd., Neihu District, Taipei 11490, Taiwan.
Ya-Wen LinGraduate Institute of Medical Sciences, National Defense Medical Center, No. 161, Sec. 6, Minquan East Rd., Neihu District, Taipei 11490, Taiwan.ORCID 0000-0002-1639-7941
Yu-Lueng ShihGraduate Institute of Medical Sciences, National Defense Medical Center, No. 161, Sec. 6, Minquan East Rd., Neihu District, Taipei 11490, Taiwan. albreb@ms28.hinet.net.ORCID 0000-0003-4629-4393
Tri-Service General Hospital · TWNational Defense Medical Center · TWTri-Service General Hospital Songshan Branch · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the most common cancers and the second leading cause of cancer-related deaths. Discrepancies in clinical outcomes are observed even among patients with same-stage CRC due to molecular heterogeneity. Thus, biomarkers for predicting prognosis in CRC patients are urgently needed. We previously demonstrated that stage II CRC patients with

Indexed as

Colorectal NeoplasmsDNA MethylationDNA, NeoplasmNeoplasm ProteinsDisease-Free SurvivalFemaleHCT116 CellsHT29 CellsHumansMaleNeoplasm StagingSurvival RateDNA, NeoplasmNeoplasm Proteinscolorectal cancer (CRC)DNA methylationLIM homeobox transcription factor 1α (LMX1A)NK6 homeobox 1 (NKX6.1)sex-determining region Y-box 1 (SOX1)zinc finger protein 177 (ZNF177)

Identifiers

PMID31547144
PMCPMC6801964
OpenAlexW2973320142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.