Evidence map›Paper›PMID 31547088›Full record

ArticleMetabolites2019

Choosing an Optimal Sample Preparation in

Julian Pezzatti, Matthieu Bergé, Julien Boccard, Santiago Codesido, Yoric Gagnebin, Patrick H Viollier, Víctor González-Ruiz, Serge Rudaz

Abstract read
In one paragraph

Article in Metabolites, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Designing optimal experiments in metabolomics.Metabolomics : Official journal of the Metabolomic Society · 2024
    Review
  4. Bacterial Metabolomics: Sample Preparation Methods.Biochemistry research international · 2022
    Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julian PezzattiInstitute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. julian.pezzatti@unige.ch.ORCID 0000-0002-3329-8240
Matthieu BergéDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, University Medical Centre, 1206 Geneva, Switzerland. matthieu.berge@unige.ch.
Julien BoccardInstitute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. julien.boccard@unige.ch.ORCID 0000-0001-5913-9566
Santiago CodesidoInstitute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. santiago.codesido@unige.ch.
Yoric GagnebinInstitute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. yoric.gagnebin@unige.ch.
Patrick H ViollierDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, University Medical Centre, 1206 Geneva, Switzerland. patrick.viollier@unige.ch.
Víctor González-RuizInstitute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. victor.gonzalez@unige.ch.ORCID 0000-0001-7204-2363
Serge RudazInstitute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. serge.rudaz@unige.ch.ORCID 0000-0002-4180-5417

Funding

Swiss Centre for Applied Human Toxicology Program 2017-2020 (Core Project 3: Neurotoxicity)Swiss National Science Foundation 31003A_166658
6 · The paper itself

Abstract

Untargeted metabolomics aims to provide a global picture of the metabolites present in the system under study. To this end, making a careful choice of sample preparation is mandatory to obtain reliable and reproducible biological information. In this study, eight different sample preparation techniques were evaluated using

Indexed as

AMOPLSdesign of experimentshigh resolution mass spectrometryhydrophilic interaction liquid chromatographyion mobility spectrometrymetabolomicssample preparation

Identifiers

PMID31547088
PMCPMC6836107

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.