Evidence map›Paper›PMID 31547059›Full record

ArticleCells2019

CPT1A Supports Castration-Resistant Prostate Cancer in Androgen-Deprived Conditions.

Molishree Joshi, Gergana E Stoykova, Maren Salzmann-Sullivan, Monika Dzieciatkowska, Lauren N Liebman, Gagan Deep, Isabel R Schlaepfer

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
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  6. Article
  7. Review
  8. Article
  9. Article
  10. Oral Microbiome and CPT1A Function in Fatty Acid Metabolism in Oral Cancer.International journal of molecular sciences · 2024
    Article
  11. Review
  12. Article
  13. Frontiers in oncology · 2024
    Article
  14. Review
  15. Expression Variation ofInternational journal of molecular sciences · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Molishree JoshiDepartment of Pharmacology, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USA. Molishree.Joshi@cuanschutz.edu.
Gergana E StoykovaDivision of Medical Oncology, University of Colorado Anschutz Medical Center. Aurora, CO 80045, USA. gergana.stoykova@ucdenver.edu.
Maren Salzmann-SullivanDivision of Medical Oncology, University of Colorado Anschutz Medical Center. Aurora, CO 80045, USA. maren.salzmann-sullivan@cuanschutz.edu.
Monika DzieciatkowskaDepartment of Biochemistry, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USA. monika.dzieciatkowska@cuanschutz.edu.
Lauren N LiebmanDivision of Medical Oncology, University of Colorado Anschutz Medical Center. Aurora, CO 80045, USA. lliebman@umich.edu.ORCID 0000-0002-3491-0788
Gagan DeepDepartment of Cancer Biology, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA. gdeep@wakehealth.edu.
Isabel R SchlaepferDivision of Medical Oncology, University of Colorado Anschutz Medical Center. Aurora, CO 80045, USA. isabel.schlaepfer@cuanschutz.edu.ORCID 0000-0002-8659-9629
University of Colorado Anschutz Medical Campus · USAtrium Health Wake Forest Baptist · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is the most common cancer in men, and the global burden of the disease is rising. The majority of PCa deaths are due to metastasis that are highly resistant to current hormonal treatments; this state is called castration-resistant prostate cancer (CRPC). In this study, we focused on the role of the lipid catabolism enzyme

Indexed as

Prostatic Neoplasms, Castration-ResistantAcetylationAndrogen AntagonistsAndrogensBenzamidesCarnitine O-PalmitoyltransferaseCell Line, TumorCell ProliferationDrug Resistance, NeoplasmHistone AcetyltransferasesHistonesHumansMaleNitrilesPhenylthiohydantoinProtein Processing, Post-TranslationalAndrogen AntagonistsAndrogensBenzamidesCarnitine O-PalmitoyltransferaseCPT1A protein, humanenzalutamideHistone AcetyltransferasesHistonesNitrilesPhenylthiohydantoinandrogen receptorCPT1Adihydrotestosteroneenzalutamidehistone acetylationprostate cancer

Identifiers

PMID31547059
PMCPMC6830347
OpenAlexW2974245500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.