Evidence map›Paper›PMID 31547039›Full record

ReviewMicromachines2019

Advancement of Peptide Nanobiotechnology via Emerging Microfluidic Technology.

Kiat Hwa Chan, Jonathan Jen Jie Tay

Open access · goldAbstract readReview
In one paragraph

Review in Micromachines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Sequential storage and release of microdroplets.Microsystems & nanoengineering · 2021
    Article
  5. Article
  6. Article
  7. Peptide-Based Nanomaterials for Tumor Immunotherapy.Molecules (Basel, Switzerland) · 2020
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Kiat Hwa ChanDivision of Science, Yale-NUS College, 16 College Avenue West, Singapore 138527, Singapore. kiathwa.chan@yale-nus.edu.sg.ORCID 0000-0002-4499-4436
Jonathan Jen Jie TayDivision of Science, Yale-NUS College, 16 College Avenue West, Singapore 138527, Singapore. e0020840@u.nus.edu.
National University of Singapore · SGYale-NUS College · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptide nanotechnology has experienced a long and enduring development since its inception. Many different applications have been conceptualized, which depends on the functional groups present on the peptide and the physical shape/size of the peptide nanostructures. One of the most prominent nanostructures formed by peptides are nanoparticles. Until recently, however, it has been challenging to engineer peptide nanoparticles with low dispersity. An emerging and promising technique involves the utility of microfluidics to produce a solution of peptide nanoparticles with narrow dispersity. In this process, two or more streams of liquid are focused together to create conditions that are conducive towards the formation of narrowly dispersed samples of peptide nanoparticles. This makes it possible to harness peptide nanoparticles for the myriad of applications that are dependent on nanoparticle size and uniformity. In this focus review, we aim to show how microfluidics may be utilized to (1) study peptide self-assembly, which is critical to controlling nanostructure shape and size, and peptide-interface interactions, and (2) generate self-assembling peptide-based microgels for miniaturized cell cultures. These examples will illustrate how the emerging microfluidic approach promises to revolutionize the production and application of peptide nanoparticles in ever more diverse fields than before.

Indexed as

low dispersitymicrofluidicsmicrogelsminiaturized cell culturesnanoparticlespeptidesself-assembly

Identifiers

PMID31547039
PMCPMC6843689
OpenAlexW2973912451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.