Evidence map›Paper›PMID 31547005›Full record

ArticleCells2019

Diverse Roads Taken by

Maria Gkiouli, Philipp Biechl, Wolfgang Eisenreich, Angela M Otto

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Isotopic tracing inVirulence · 2026
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  17. Article
  18. Correlation Between von Hippel-Lindau Gene Expression and Tumor SUVmax and Survival Prognosis in Hepatocellular Carcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maria GkiouliMunich School of BioEngineering, Technical University of Munich, 85748 Garching, Germany. mariagkiouli@gmail.com.
Philipp BiechlMunich School of BioEngineering, and Department of Chemistry, Chair of Biochemistry, Technical University of Munich, 85748 Garching, Germany. philipp.biechl@tum.de.
Wolfgang EisenreichDepartment of Chemistry, Chair of Biochemistry, Technical University of Munich, 85748 Garching, Germany. wolfgang.eisenreich@mytum.de.
Angela M OttoMunich School of BioEngineering, Technical University of Munich, 85748 Garching, Germany. otto@tum.de.
Technical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In cancers, tumor cells are exposed to fluctuating nutrient microenvironments with limiting supplies of glucose and glutamine. While the metabolic program has been related to the expression of oncogenes, only fractional information is available on how variable precarious nutrient concentrations modulate the cellular levels of metabolites and their metabolic pathways. We thus sought to obtain an overview of the metabolic routes taken by

Indexed as

Breast NeoplasmsCarbon IsotopesCitric Acid CycleDose-Response Relationship, DrugFemaleGlucoseGlutamic AcidGlutamineGlycolysisHumansLactic AcidMalatesMCF-7 CellsMetabolic Networks and PathwaysPyruvic AcidTumor MicroenvironmentCarbon-13Carbon IsotopesGlucoseGlutamic AcidGlutamineLactic AcidMalatesmalic acidPyruvic Acid13C-metabolitesanaplerosisbreast cancer cellsgluconeogenesisglycolysisisotopologue distributionnutrient deprivationTCA cycleWarburg effect

Identifiers

PMID31547005
PMCPMC6829299
OpenAlexW2973433881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.