Evidence map›Paper›PMID 31546928›Full record

ArticleInternational journal of molecular sciences2019

Viscoelastic Behavior of Embroidered Scaffolds for ACL Tissue Engineering Made of PLA and P(LA-CL) After In Vitro Degradation.

Judith Hahn, Gundula Schulze-Tanzil, Michaela Schröpfer, Michael Meyer, Clemens Gögele, Mariann Hoyer, Axel Spickenheuer, Gert Heinrich, Annette Breier

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Embroidered Silk Fibroin Scaffolds for ACL Tissue Engineering.International journal of molecular sciences · 2025
    Article
  3. Strategies to Enhance Protein Delivery.Langmuir : the ACS journal of surfaces and colloids · 2025
    Review
  4. Review
  5. Article
  6. Tendon mechanobiology in the context of tendon biofabrication.Frontiers in bioengineering and biotechnology · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. In focus in HCB.Histochemistry and cell biology · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Judith HahnLeibniz-Institut für Polymerforschung Dresden e. V., 01069 Dresden, Germany. hahn-judith@ipfdd.de.ORCID 0000-0003-0362-9018
Gundula Schulze-TanzilInstitute of Anatomy and Cell Biology, Paracelsus Medical Private University, Salzburg and Nuremberg, 90419 Nuremberg, Germany. gundula.schulze@pmu.ac.at.ORCID 0000-0002-9807-9532
Michaela SchröpferForschungsinstitut für Leder und Kunststoffbahnen (FILK) gGmbH, 09599 Freiberg, Germany. michaela.schroepfer@filkfreiberg.de.
Michael MeyerForschungsinstitut für Leder und Kunststoffbahnen (FILK) gGmbH, 09599 Freiberg, Germany. michael.meyer@filkfreiberg.de.
Clemens GögeleInstitute of Anatomy and Cell Biology, Paracelsus Medical Private University, Salzburg and Nuremberg, 90419 Nuremberg, Germany. clemens.goegele@pmu.ac.at.
Mariann HoyerAmedes MVZ für Laboratoriumsdiagnostik und Mikrobiologie Halle/Leipzig GmbH, 06112 Halle, Germany. mariann.hoyer@amedes-group.com.
Axel SpickenheuerLeibniz-Institut für Polymerforschung Dresden e. V., 01069 Dresden, Germany. spickenheuer@ipfdd.de.
Gert HeinrichLeibniz-Institut für Polymerforschung Dresden e. V., 01069 Dresden, Germany. gheinrich@ipfdd.de.
Annette BreierLeibniz-Institut für Polymerforschung Dresden e. V., 01069 Dresden, Germany. breier@ipfdd.de.

Funding

Deutsche Forschungsgemeinschaft BR 1886/6-1Deutsche Forschungsgemeinschaft BR 5604/1-1Deutsche Forschungsgemeinschaft HE 4466/22-1Deutsche Forschungsgemeinschaft ME 3734/2-1Deutsche Forschungsgemeinschaft ME 3734/5-1Deutsche Forschungsgemeinschaft SCHU 1979/14-1Deutsche Forschungsgemeinschaft SCHU 1979/9-1
6 · The paper itself

Abstract

A rupture of the anterior cruciate ligament (ACL) is the most common knee ligament injury. Current applied reconstruction methods have limitations in terms of graft availability and mechanical properties. A new approach could be the use of a tissue engineering construct that temporarily reflects the mechanical properties of native ligament tissues and acts as a carrier structure for cell seeding. In this study, embroidered scaffolds composed of polylactic acid (PLA) and poly(lactic-co-ε-caprolactone) (P(LA-CL)) threads were tested mechanically for their viscoelastic behavior under in vitro degradation. The relaxation behavior of both scaffold types (

Indexed as

Tissue EngineeringAnimalsAnterior Cruciate LigamentAnterior Cruciate Ligament InjuriesCells, CulturedElasticityPolyestersRabbitsTissue ScaffoldsViscositylactide-caprolactone copolymerPolyesterspoly(lactide)anterior cruciate ligamentcytoskeletonembroidered scaffoldligamentocytesPLAP(LA-CL)tissue engineeringviscoelastic behavior

Identifiers

PMID31546928
PMCPMC6770114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.