ArticleMaterials (Basel, Switzerland)2019
Comparative Cytocompatibility and Mineralization Potential of Bio-C Sealer and TotalFill BC Sealer.
Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed.
- Effect of continuous wave of condensation on postoperative pain using bioceramic versus resin sealers: a randomized clinical trial.BMC oral health · 2026Trial
- Trial
- Clinical and radiological outcomes of Thermafil Plus used with bioceramic versus epoxy-resin sealer: results from a 12-month randomized clinical trial.Odontology · 2026Article
- Physiochemical properties of premixed bioceramic-based root canal sealer reinforced with copper oxide nanoparticles.Journal of conservative dentistry and endodontics · 2026Article
- Effect of Powder-to-Liquid Ratio on pH, Calcium Ion Release, and Solubility Behaviors of Endodontic Bioceramics: An In Vitro Study.Journal of functional biomaterials · 2026Article
- Setting Characteristics, Solubility, Bioactivity and Interaction with Dentin of Four Calcium Silicate-Based Endodontic Sealers.Journal of functional biomaterials · 2026Article
- Oxidative Stress, Pro-Inflammatory Response, Cytotoxicity and Apoptosis Induced by Contemporary Endodontic Sealers in Human Periodontal Ligament Fibroblasts.Journal of functional biomaterials · 2026Article
- Cytotoxicity of Root Canal Sealers and Potential Clinical Implications: A Comprehensive Systematic Review of In Vitro Studies.Journal of clinical medicine · 2026Review
- Effect of dentine moisture conditions on interfacial adaptation of a calcium silicate-based sealer compared with an epoxy resin-based sealer: an SEM/EDX analysis.Biomaterial investigations in dentistry · 2026Article
- Micro-computed tomography evaluation of sonically or ultrasonically activated irrigation on the removal of tricalcium silicate-based intracanal dressing.Journal of conservative dentistry and endodontics · 2025Article
- Studying How Calcium Silicate and Radiopacifier Proportions Affect the Physicochemical Properties of Endodontic Calcium Silicate-Based Sealers.Materials (Basel, Switzerland) · 2025Article
- Bond Strength of an Epoxy Resin Root Canal Sealer Prototype.Dentistry journal · 2025Article
- In vitro Evaluation of Cytotoxicity, Biocompatibility, and Osteogenic Effect of Two Calcium Silicate Sealers Compared with AH Plus Jet.European journal of dentistry · 2025Article
- Biocompatibility and bioactivity of bioceramic endodontic sealer: NeoSealer Flo.Journal of applied oral science : revista FOB · 2025Article
- Root Development Following Bioceramic Material Application in Immature Permanent Teeth: A Case Series With 24-Month Follow-Up.Case reports in dentistry · 2025Article
- Clinical outcomes of nonsurgical root canal treatment using NeoSealer Flo and Endosequence BC Sealer: A retrospective analysis with short-term follow-up.Clinical oral investigations · 2024Article
- An Evaluation of the Cytocompatibility of Endodontic Bioceramics in Human Periodontal-Ligament-Derived Cells.Journal of functional biomaterials · 2024Article
- Article
- Biocompatibility, bioactivity and immunomodulatory properties of three calcium silicate-based sealers: an in vitro study on hPDLSCs.Clinical oral investigations · 2024Article
- Evaluation of the antibacterial and cytotoxic properties of TotalFill and NeoSEALER flo bioceramic sealers.Journal of conservative dentistry and endodontics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The aim of this study was to investigate the cytocompatibility and mineralization potential of two premixed hydraulic endodontic sealers compared with an epoxy resin-based root canal sealer. The cellular responses and mineralization capacity were studied in human periodontal ligament stem cells (hPDLSCs) that were exposed to premixed hydraulic sealers, Bio-C Sealer (Angelus, Londrína, PR, Brazil), TotalFill BC Sealer (FKG Dentaire SA, La-Chaux-de-fonds, Switzerland) and an epoxy resin-based material, AH Plus (Dentsply De Trey, Konstanz, Germany). Non-exposed cultures served as the control. The endodontic sealers were assessed using scanning electron microscopy (SEM) and energy dispersive X-ray microanalysis (EDX). Statistical analyses were done using Analisis of Variance (ANOVA), with Bonferroni adjusted pairwise comparison (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.