Evidence map›Paper›PMID 31546691›Full record

ArticleBiomolecules2019

Iso-Mukaadial Acetate from

Nontokozo Z Msomi, Francis O Shode, Ofentse J Pooe, Sithandiwe Mazibuko-Mbeje, Mthokozisi B C Simelane

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Nontokozo Z MsomiSchool of Life Sciences, University of KwaZulu-Natal, Durban, Westville 4000, South Africa. ntokozomsomi0@gmail.com.
Francis O ShodeDepartment of Biotechnology and Food Technology, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa. francisshode@gmail.com.
Ofentse J PooeSchool of Life Sciences, University of KwaZulu-Natal, Durban, Westville 4000, South Africa. PooeO@ukzn.ac.za.ORCID 0000-0002-2967-7846
Sithandiwe Mazibuko-MbejeBiomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg 7505, South Africa. Sithandiwe.Mazibuko@mrc.ac.za.ORCID 0000-0002-0946-8027
Mthokozisi B C SimelaneDepartment of Biochemistry, Faculty of Science, University of Johannesburg, Auckland Park 2092, Johannesburg 2006, South Africa. msimelane@uj.ac.za.ORCID 0000-0002-7798-3020
University of KwaZulu-Natal · ZADurban University of Technology · ZASouth African Medical Research Council · ZAUniversity of Johannesburg · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder which has become a major risk to the health of humankind, as its global prevalence is increasing rapidly. Currently available treatment options in modern medicine have several adverse effects. Thus, there is an urgent need to develop alternative cost-effective, safe, and active treatments for diabetes. In this regard, medicinal plants provide the best option for new therapeutic remedies desired to be effective and safe. Recently, we focused our attention on drimane sesquiterpenes as potential sources of antimalarial and antidiabetic agents. In this study, iso-mukaadial acetate (Iso) (

Indexed as

AMP-Activated Protein KinasesAnimalsCell LineCell SurvivalDose-Response Relationship, DrugGlucoseMagnoliopsidaMyoblasts, SkeletalPlant BarkPlant ExtractsPolycyclic SesquiterpenesProto-Oncogene Proteins c-aktRatsAMP-Activated Protein KinasesGlucosePlant ExtractsPolycyclic SesquiterpenesProto-Oncogene Proteins c-aktAKTAMPKantidiabetic activityglucose utilisationiso-mukaadial acetateWarburgia salutaris

Identifiers

PMID31546691
PMCPMC6843169
OpenAlexW2974403277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.