Evidence map›Paper›PMID 31546679›Full record

ArticleGenes2019

Transcriptomic Signatures of Experimental Alkaloid Consumption in a Poison Frog.

Eugenia Sanchez, Ariel Rodríguez, Jose H Grau, Stefan Lötters, Sven Künzel, Ralph A Saporito, Eva Ringler, Stefan Schulz, Katharina C Wollenberg Valero, Miguel Vences

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Rapid toxin sequestration modifies poison frog physiology.The Journal of experimental biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 4 countries.

Eugenia SanchezZoological Institute, Technische Universität Braunschweig, 38106 Braunschweig, Germany. eu.sanisa@gmail.com.ORCID 0000-0002-9145-3608
Ariel RodríguezInstitut fur Zoologie, Tierärztliche Hochschule Hannover, 30559 Hannover, Germany. Ariel.Rodriguez@tiho-hannover.de.ORCID 0000-0003-1936-793X
Jose H GrauMuseum für Naturkunde Berlin, Leibniz-Institut für Evolutions- und Biodiversitätsforschung, 10115 Berlin, Germany. jh.grau.jipoulou@gmail.com.
Stefan LöttersBiogeography Department, Trier University, 54296 Trier, Germany. loetters@uni-trier.de.
Sven KünzelDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, 24306 Plön, Germany. kuenzel@evolbio.mpg.de.
Ralph A SaporitoDepartment of Biology, John Carroll University, University Heights, OH 44118, USA. rsaporito@jcu.edu.
Eva RinglerMesserli Research Institute, University of Veterinary Medicine Vienna, Medical University of Vienna, and University of Vienna, A-1210 Vienna, Austria. eva.ringler@univie.ac.at.ORCID 0000-0003-3273-6568
Stefan SchulzInstitute of Organic Chemistry, Technische Universität Braunschweig, 38106 Braunschweig, Germany. stefan.schulz@tu-bs.de.ORCID 0000-0002-4810-324X
Katharina C Wollenberg ValeroDepartment of Biological and Marine Sciences, University of Hull, Kingston-Upon Hull 01482, UK. kc.wollenberg@gmail.com.ORCID 0000-0001-8858-1804
Miguel VencesZoological Institute, Technische Universität Braunschweig, 38106 Braunschweig, Germany. m.vences@tu-bs.de.ORCID 0000-0003-0747-0817
Technische Universität Braunschweig · DEJohn Carroll University · USMax Planck Institute for Evolutionary Biology · DEMuseum für Naturkunde · DEUniversität Trier · DEUniversity of Hull · GBUniversity of Veterinary Medicine Hannover, Foundation · DEUniversity of Vienna · AT

Funding

Austrian Science Fund FWF T 699
6 · The paper itself

Abstract

In the anuran family Dendrobatidae, aposematic species obtain their toxic or unpalatable alkaloids from dietary sources, a process known as sequestering. To understand how toxicity evolved in this family, it is paramount to elucidate the pathways of alkaloid processing (absorption, metabolism, and sequestering). Here, we used an exploratory skin gene expression experiment in which captive-bred dendrobatids were fed alkaloids. Most of these experiments were performed with

Indexed as

AnimalsAnuraBridged Bicyclo Compounds, HeterocyclicGene Expression RegulationPyridinesSkinSparteineTranscriptomeBridged Bicyclo Compounds, HeterocyclicepibatidinePyridinesSparteineAllobatesAromobatidaeDendrobatesDendrobatidaeepibatidinefeeding experimentgene expressionimmune systemresistance

Identifiers

PMID31546679
PMCPMC6827147
OpenAlexW2974673952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.