Evidence map›Paper›PMID 31546170›Full record

ArticleRedox biology2020

Human aquaporin-11 guarantees efficient transport of H

Stefano Bestetti, Mauro Galli, Ilaria Sorrentino, Paolo Pinton, Alessandro Rimessi, Roberto Sitia, Iria Medraño-Fernandez

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it, 118 citations in OpenAlex.

  1. Pooled it
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  16. Fundamentals of redox regulation in biology.Nature reviews. Molecular cell biology · 2024
    Review
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  18. Article
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Stefano BestettiProtein Transport and Secretion Unit, Division of Genetics and Cell Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132, Milan, Italy.
Mauro GalliProtein Transport and Secretion Unit, Division of Genetics and Cell Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132, Milan, Italy.
Ilaria SorrentinoProtein Transport and Secretion Unit, Division of Genetics and Cell Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132, Milan, Italy.
Paolo PintonDepartment of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121, Ferrara, Italy.
Alessandro RimessiDepartment of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121, Ferrara, Italy.
Roberto SitiaProtein Transport and Secretion Unit, Division of Genetics and Cell Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132, Milan, Italy. Electronic address: sitia.roberto@hsr.it.
Iria Medraño-FernandezProtein Transport and Secretion Unit, Division of Genetics and Cell Biology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale San Raffaele, Università Vita-Salute San Raffaele, 20132, Milan, Italy. Electronic address: medranofernandez.iria@hsr.it.
Vita-Salute San Raffaele University · ITUniversity of Ferrara · ITIRCCS Ospedale San Raffaele · IT

Funding

Telethon GGP15059
6 · The paper itself

Abstract

Hydrogen peroxide (H

Indexed as

AnimalsAquaporinsBiological TransportCell MembraneChlorocebus aethiopsCHO CellsCOS CellsCricetulusDown-RegulationEndoplasmic ReticulumHEK293 CellsHeLa CellsHumansHydrogen PeroxideAQP11 protein, humanAquaporinsHydrogen PeroxideAquaporinsEndoplasmic reticulumHydrogen peroxideMembrane permeabilityPeroxiporinsRedox homeostasis

Identifiers

PMID31546170
PMCPMC6812059
OpenAlexW2973116218

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.