Evidence map›Paper›PMID 31545924›Full record

ArticleAmerican journal of physiology. Renal physiology2019

Renal SGLT mRNA expression in human health and disease: a study in two cohorts.

Vikas Srinivasan Sridhar, Jaya Prakash N Ambinathan, Matthias Kretzler, Laura L Pyle, Petter Bjornstad, Sean Eddy, David Z Cherney, Heather N Reich, European Renal cDNA Bank (ERCB);, Nephrotic Syndrome Study Network (NEPTUNE)

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The Effects of SGLT2 Inhibitors on Blood Pressure and Other Cardiometabolic Risk Factors.International journal of molecular sciences · 2024 · on this map
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. SodiumKidney medicine · 2022
    Article
  10. The sugar daddy: the role of the renal proximal tubule in glucose homeostasis.American journal of physiology. Cell physiology · 2022
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Vikas Srinivasan SridharToronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.
Jaya Prakash N AmbinathanToronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.
Matthias KretzlerDivision of Nephrology, Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
Laura L PyleDivision of Endocrinology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado.
Petter BjornstadDivision of Endocrinology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado.
Sean EddyDivision of Nephrology, Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.
David Z CherneyToronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.
Heather N ReichToronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.
European Renal cDNA Bank (ERCB);
Nephrotic Syndrome Study Network (NEPTUNE)
Toronto General Hospital · CAUniversity Health Network · CAUniversity of Colorado Denver · USUniversity of Michigan–Ann Arbor · US

Funding

The Impact of COVID-19 on People Living with Rare Diseases and Their FamiliesU2CTR002818 · NCATS · CINCINNATI CHILDRENS HOSP MED CTR · PI Maurizio Macaluso · 2019 to 2026
$51.2M
Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
Training Program in Clinical & Translationa Research in Human Glomerular DiseaseU54DK083912 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GIPSON, DEBBIE S · 2009 to 2023
$20.3M
University of Michigan O'Brien Kidney Translational Core CenterP30DK081943 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KRETZLER, MATTHIAS · 2008 to 2022
$12.9M
Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes StudyK23DK116720 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BJORNSTAD, PETTER · 2018 to 2022
$963k
NCATS NIH HHS U2C TR002818NCATS NIH HHS UL1 TR002548NIDDK NIH HHS K23 DK116720NIDDK NIH HHS P30 DK081943NIDDK NIH HHS U54 DK083912
6 · The paper itself

Abstract

Pharmacological Na

Indexed as

AdultCohort StudiesDiabetic NephropathiesFemaleGene Expression RegulationGlomerulonephritisHumansMaleMiddle AgedRNA, MessengerSodium-Glucose Transporter 1Sodium-Glucose Transporter 2RNA, MessengerSLC5A1 protein, humanSLC5A2 protein, humanSodium-Glucose Transporter 1Sodium-Glucose Transporter 2chronic kidney diseasediabetesEuropean Renal cDNA bankglomerulonephritismRNANephrotic Syndrome Study Networksodium-glucose linked cotransporter

Identifiers

PMID31545924
PMCPMC6879935
OpenAlexW2976236713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.