Trial reportCirculation2019
Effect of Transdermal Testosterone and Oral Progesterone on Drug-Induced QT Interval Lengthening in Older Men: A Randomized, Double-Blind, Placebo-Controlled Crossover-Design Study.
Trial report in Circulation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02513940 (Influence of Testosterone Administration on Drug-Induced QT Interval Prolongation and Torsades de Pointes), which is not on this map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of Testosterone Administration on Drug-Induced QT Interval Prolongation and Torsades de Pointes
Who cites it
12 citing papers in PubMed.
- Transdermal Testosterone Attenuates Drug-Induced Lengthening of Both Early and Late Ventricular Repolarization in Older Men.Clinical pharmacology and therapeutics · 2021Trial
- Male hypogonadism in patients on maintenance hemodiafiltration: prevalence and therapeutic effect.Frontiers in endocrinology · 2026Article
- Sex Hormone Profiles in Patients With Torsades de Pointes Ventricular Tachycardia: A Clinical-Electrophysiological Translational Study.JACC. Clinical electrophysiology · 2025Article
- Dihydrotestosterone Pretreatment Diminishes the Severity of Drug-Induced Torsades de Pointes.Journal of cardiovascular pharmacology · 2025Article
- Transgender-Affirming Hormone Therapies, QT Prolongation, and Cardiac Repolarization.JAMA network open · 2025Article
- Sex and Gender Differences in Ventricular Arrhythmias.US cardiology · 2023Review
- Sex-related differences in incidence, phenotype and risk of sudden cardiac death in inherited arrhythmia syndromes.Frontiers in cardiovascular medicine · 2022Review
- Cardiovascular risk and testosterone - from subclinical atherosclerosis to lipoprotein function to heart failure.Reviews in endocrine & metabolic disorders · 2021Review
- Testosterone use and shorter electrocardiographic QT interval duration in men living with and without HIV.HIV medicine · 2021Article
- Sexual Dimorphisms, Anti-Hormonal Therapy and Cardiac Arrhythmias.International journal of molecular sciences · 2021Review
- The Link Between Sex Hormones and Susceptibility to Cardiac Arrhythmias: From Molecular Basis to Clinical Implications.Frontiers in cardiovascular medicine · 2021Review
- Current National and International Guidelines for the Management of Male Hypogonadism: Helping Clinicians to Navigate Variation in Diagnostic Criteria and Treatment Recommendations.Endocrinology and metabolism (Seoul, Korea) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.