Evidence map›Paper›PMID 31545582›Full record

ArticleACS applied materials & interfaces2019

VIPER

Erin Morgan, Julia Doh, Kimberly Beatty, Norbert Reich

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Erin MorganDepartment of Chemistry and Biochemistry , University of California Santa Barbara , Santa Barbara , California 93117 , United States.ORCID http://orcid.org/0000-0003-0043-889X
Norbert ReichDepartment of Chemistry and Biochemistry , University of California Santa Barbara , Santa Barbara , California 93117 , United States.ORCID http://orcid.org/0000-0001-6032-2704
Oregon Health & Science University · USUniversity of California, Santa Barbara · US

Funding

New Technology for Tracking Proteins by Light and Electron MicroscopyR01GM122854 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI BEATTY, KIMBERLY ELIZABETH · 2017 to 2021
$2.1M
NIR Light-Activated Nanoparticles for Drug and Gene DeliveryR01EB012637 · NIBIB · UNIVERSITY OF MINNESOTA · PI ZASADZINSKI, JOSEPH ANTHONY · 2011 to 2014
$1.3M
Two-Photon Microscopy for Biomedical ResearchS10RR022585 · NCRR · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI REESE, BENJAMIN E · 2007 to 2007
$500k
NCRR NIH HHS S10 RR022585NIBIB NIH HHS R01 EB012637NIGMS NIH HHS R01 GM122854
6 · The paper itself

Abstract

Tracking intracellular proteins in live cells has many challenges. The most widely used method, fluorescent protein fusions, can track proteins in their native cellular environment and has led to significant discoveries in cell biology. Fusion proteins add steric bulk to the target protein and can negatively affect native protein function. The use of exogenous probes such as antibodies or protein labels is problematic because these cannot cross the plasma membrane on their own and thus cannot label intracellular targets in cells. We developed a labeling platform, VIPER

Indexed as

Cell SurvivalDrug LiberationEndocytosisFluorescent DyesGoldHeLa CellsHumansIntracellular SpaceLasersNanoshellsParticle SizePeptidesProtein TransportStaining and LabelingFluorescent DyesGoldPeptidescoiled coilhollow gold nanoshellslive cell imagingpeptide deliveryprotein tagging

Identifiers

PMID31545582
PMCPMC7351371
OpenAlexW2976766645

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.