Evidence map›Paper›PMID 31544800›Full record

SynthesisJournal of genetics2019

Association between genetic polymorphisms of long noncoding RNA H19 and cancer risk: a meta-analysis.

Mohammad Hashemi, Abdolkarim Moazeni-Roodi, Sahel Sarabandi, Shima Karami, Saeid Ghavami

Abstract readMeta-AnalysisReview
PubMed
In one paragraph

Synthesis in Journal of genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Non-Coding RNAs Extended Omnigenic Module of Cancers.Entropy (Basel, Switzerland) · 2024
    Article
  4. Efficacy of metformin adjunctive therapy as the treatment for non-diabetic patients with advanced non-small cell lung cancer: A Systematic review and Meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Identification and characterization of functional long noncoding RNAs in cancer.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Review
  14. Exosomal Long Non-Coding RNAs in Lung Diseases.International journal of molecular sciences · 2020
    Review
  15. Genetic association betweenJournal of genetics · 2020
    Review
  16. Genetic Variant in Long Non-Coding RNAFrontiers in oncology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Mohammad HashemiGenetics of Non-communicable Disease Research Centre, Zahedan University of Medical Sciences, Zahedan 9816743181, Iran. mhd.hashemi@gmail.com; hashemim@zaums.ac.ir.
Abdolkarim Moazeni-Roodi
Sahel Sarabandi
Shima Karami
Saeid Ghavami
Zahedan University of Medical Sciences · IRIranshahr University · IRResearch Institute in Oncology and Hematology · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNA (lncRNA) H19, a well-known oncogenic lncRNA, is overexpressed in various cancers. Several studies have investigated the association between polymorphisms in lncRNA H19 and the risk of various cancer types; however, the findings were inconsistent. In this study, we performed a meta-analysis to identify the precise association between H19 polymorphisms and cancer risk. Appropriate studies were retrieved from searching Web of Science, PubMed, Scopus, and Google scholar databases, updated 25 November 2018. The pooled odds ratios (ORs with 95% confidence intervals (CIs) were calculated to estimate the strength of the association between H19 polymorphisms and cancer risk. Our findings revealed that the H19-rs217727 C>T polymorphism is significantly associated with an increased risk of overall cancer in homozygous codominant (OR=1.28, 95% CI=1.04-1.57,

Indexed as

Polymorphism, Single NucleotideCarcinoma, Squamous CellGastrointestinal NeoplasmsGenetic Predisposition to DiseaseHumansLung NeoplasmsMouth NeoplasmsNeoplasmsRisk FactorsRNA, Long NoncodingH19 long non-coding RNARNA, Long Noncoding

Identifiers

PMID31544800
OpenAlexW2965346183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.