Evidence map›Paper›PMID 31544789›Full record

ArticleJournal of genetics2019

Shaik Mohammad Naushad, Akella Radha Rama Devi, Tajamul Hussain, Salman A Alrokayan, M Janaki Ramaiah, Vijay Kumar Kutala

Abstract read
PubMed
In one paragraph

Article in Journal of genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Shaik Mohammad NaushadSandor Specialty Diagnostics, Banjara Hills, Road No 3, Hyderabad 500 034, India. naushadsm@gmail.com.
Akella Radha Rama Devi
Tajamul Hussain
Salman A Alrokayan
M Janaki Ramaiah
Vijay Kumar Kutala
King Saud University · SANizam's Institute of Medical Sciences · INSASTRA University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In view of the documented association of solute carrier family 19 member 1 (SLC19A1) G80A (R27H) polymorphism with the risk for different types of cancers and systemic lupus erythematosus (SLE), we have reanalysed the case-control study on breast cancer to ascertain the conditions in which this polymorphic variant exerts the risk of breast cancer. Association statistics have revealed that this polymorphism exerts the risk for breast cancer under the conditions of low folate intake, and in the absence of well-documented protective polymorphism in cytosolic serine hydroxymethyltransferase. To substantiate this observation, we have developed a homology model of SLC19A1 using glycerol-3-phosphate transporter (d1pw4a) as a template where 73% of the residues were modelled at 90% confidence while 162 residues were modelled

Indexed as

AntiportersBinding SitesBreast NeoplasmsCase-Control StudiesComputer SimulationFolic AcidGlycine HydroxymethyltransferaseHumansMethotrexateModels, MolecularMonosaccharide Transport ProteinsPolymorphism, GeneticProtein Structure, SecondaryProtein Structure, TertiaryReduced Folate Carrier ProteinRisk FactorsAntiportersFolic Acidglucose 6-phosphate(transporter)Glycine HydroxymethyltransferaseMethotrexateMonosaccharide Transport ProteinsReduced Folate Carrier ProteinSLC19A1 protein, human

Identifiers

PMID31544789
OpenAlexW2969725160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.