Trial reportTwin research and human genetics : the official journal of the International Society for Twin Studies2019
IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies - An Update.
Trial report in Twin research and human genetics : the official journal of the International Society for Twin Studies, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 27 citations in OpenAlex.
- Heritability of Fruit and Vegetable Consumption and Depressive Symptoms in Community-Based Middle-Aged and Older Adults from Four International Twin Cohorts.Behavior genetics · 2026Article
- Evaluating a Genome-Wide Polygenic Score for Handgrip Strength and Its Interplay with Leisure-Time Physical Activity Across the IGEMS Twin Cohorts.Medicine and science in sports and exercise · 2026Article
- Article
- The Interplay of Genes and Environment Across Multiple Studies (IGEMS) Consortium After Fifteen Years.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2026Article
- The long reach of childhood income inequality: a multinational twin study of gene-environment interplay on adult depressive symptoms.Psychological medicine · 2026Article
- Moderating effects of educational inequality on education polygenic scores, attained education and dementia-risk relationships.SSM - population health · 2026Article
- Interaction between genetic predisposition to successful ageing and chronic air pollution on lung disease in elderly women: results of the German SALIA cohort.BMJ open respiratory research · 2025Article
- Genetic and environmental influences on alcohol consumption in middle to late life.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025Article
- Is educational attainment protective against developing dementia? A twin study of genetic and environmental contributions.European journal of epidemiology · 2025Article
- Profiling Plasma Biomarkers, Particularly pTau217 and pTau217/Aβ42, and Their Relation to Cognition in Memory Clinic Patients.Journal of neurochemistry · 2025Article
- Terminal Increases in Depressive Symptoms in a Multinational Twin Consortium.Psychological science · 2025Article
- Both childhood and adult perceived financial strain impact age trajectories of change in emotional health in late adulthood.Aging & mental health · 2025Observational
- Self-rated health and mortality: family background and genetic precursors.Discover social science and health · 2025Article
- Longitudinal associations between fruit and vegetable intakes and depressive symptoms in middle-aged and older adults from four international twin cohorts.Scientific reports · 2024Article
- Age and Sex Differences in the Genetic Architecture of Measures of Subjective Health: Relationships With Physical Health, Depressive Symptoms, and Episodic Memory.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Longitudinal analyses indicate bidirectional associations between loneliness and health.Aging & mental health · 2023Article
- Does sleep duration moderate genetic and environmental contributions to cognitive performance?Sleep · 2022Article
- Estimating Likelihood of Dementia in the Absence of Diagnostic Data: A Latent Dementia Index in 10 Genetically Informed Studies.Journal of Alzheimer's disease : JAD · 2022Article
- Genetic and Environmental Influences on Semantic Verbal Fluency Across Midlife and Later Life.Behavior genetics · 2021Article
- The NAS-NRC Twin Registry and Duke Twins Study of Memory in Aging: An Update.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 14 institutions in 5 countries.
Funding
Abstract
The Interplay of Genes and Environment across Multiple Studies (IGEMS) is a consortium of 18 twin studies from 5 different countries (Sweden, Denmark, Finland, United States, and Australia) established to explore the nature of gene-environment (GE) interplay in functioning across the adult lifespan. Fifteen of the studies are longitudinal, with follow-up as long as 59 years after baseline. The combined data from over 76,000 participants aged 14-103 at intake (including over 10,000 monozygotic and over 17,000 dizygotic twin pairs) support two primary research emphases: (1) investigation of models of GE interplay of early life adversity, and social factors at micro and macro environmental levels and with diverse outcomes, including mortality, physical functioning and psychological functioning; and (2) improved understanding of risk and protective factors for dementia by incorporating unmeasured and measured genetic factors with a wide range of exposures measured in young adulthood, midlife and later life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.