Evidence map›Paper›PMID 31544622›Full record

ArticleStatistical methods in medical research2020

Quantile contours and allometric modelling for risk classification of abnormal ratios with an application to asymmetric growth-restriction in preterm infants.

Marco Geraci, Nansi S Boghossian, Alessio Farcomeni, Jeffrey D Horbar

Abstract read
In one paragraph

Article in Statistical methods in medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Integration and the Developmental Genetics of Allometry.Integrative and comparative biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marco GeraciDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.ORCID 0000-0002-6311-8685
Nansi S BoghossianDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Alessio FarcomeniDepartment of Economics and Finance, University of Rome Tor Vergata, Rome, Italy.ORCID 0000-0002-7104-5826
Jeffrey D HorbarDepartment of Pediatrics, College of Medicine, University of Vermont, Burlington, VT, USA.

Funding

Modeling and estimation of nonlinear quantile effects in child health researchR03HD084807 · NICHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI GERACI, MARCO · 2016 to 2017
$147k
NICHD NIH HHS R03 HD084807
6 · The paper itself

Abstract

We develop an approach to risk classification based on quantile contours and allometric modelling of multivariate anthropometric measurements. We propose the definition of allometric direction tangent to the directional quantile envelope, which divides ratios of measurements into half-spaces. This in turn provides an operational definition of directional quantile that can be used as cutoff for risk assessment. We show the application of the proposed approach using a large dataset from the Vermont Oxford Network containing observations of birthweight (BW) and head circumference (HC) for more than 150,000 preterm infants. Our analysis suggests that disproportionately growth-restricted infants with a larger HC-to-BW ratio are at increased mortality risk as compared to proportionately growth-restricted infants. The role of maternal hypertension is also investigated.

Indexed as

Infant, PrematureBirth WeightCephalometryHumansInfantInfant, NewbornBrain-sparingchild healthgrowth restrictionindex ratioisoprobability contoursprincipal component analysis

Identifiers

PMID31544622
PMCPMC7085954

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.