Evidence map›Paper›PMID 31544479›Full record

ArticleAIDS research and human retroviruses

Higher Risks of Virologic Failure and All-Cause Deaths Among Older People Living with HIV in Chongqing, China.

Guohui Wu, Chao Zhou, Xiangjun Zhang, Wei Zhang, Rongrong Lu, Lin Ouyang, Hui Xing, Yiming Shao, Yuhua Ruan, Han-Zhu Qian

Abstract readComparative Study
In one paragraph

Article in AIDS research and human retroviruses. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guohui WuChongqing Municipal Center for Disease Control and Prevention, Chongqing, China.
Chao ZhouChongqing Municipal Center for Disease Control and Prevention, Chongqing, China.
Xiangjun ZhangSchool of Community Health Sciences, University of Nevada, Reno, Reno, Nevada.
Wei ZhangChongqing Municipal Center for Disease Control and Prevention, Chongqing, China.
Rongrong LuChongqing Municipal Center for Disease Control and Prevention, Chongqing, China.
Lin OuyangChongqing Municipal Center for Disease Control and Prevention, Chongqing, China.
Hui XingState Key Laboratory of Infectious Disease Prevention and Control (SKLID), Chinese Center for Disease Control and Prevention (China CDC), Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing, China.
Yiming ShaoState Key Laboratory of Infectious Disease Prevention and Control (SKLID), Chinese Center for Disease Control and Prevention (China CDC), Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing, China.
Yuhua RuanState Key Laboratory of Infectious Disease Prevention and Control (SKLID), Chinese Center for Disease Control and Prevention (China CDC), Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing, China.
Han-Zhu QianShanghai Jiao Tong University-Yale Joint Center for Biostatistics and Data Science, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Older people living with HIV (PLWH) may have delayed diagnosis and access to care and therefore have poorer disease outcomes. Little is known about HIV care and disease outcomes among older PLWH in China. This retrospective cohort study used data from all adult HIV/AIDS cases during 1988-2017 in Chongqing, China from two national databases. We compared demographic and behavioral profiles, HIV care, virologic suppression, and mortality between two age groups of 18-49 and ≥50 years. Multivariate logistic and cox regression analyses were used to calculate adjusted odds ratio (AOR) and adjusted hazard ratio (AHR) among older versus younger PLWH. Of 46,580 adult HIV/AIDS cases, 76.1% were men and 38.2% were 50 years of age or older. The proportion of older cases in men increased from 2.4% in 2002 to 51.8% in 2017, and in women from 3.3% to 57.9%. Older PLWH had a lower CD4 count than their younger counterparts at HIV diagnosis (median 323 vs. 391 cells/μL;

Indexed as

MortalityAdolescentAdultAgedAged, 80 and overAge FactorsAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountChinaFemaleHIV InfectionsHumansMaleMiddle AgedOdds RatioAnti-HIV Agentsall-cause mortalityantiretroviral therapyChinaHIVolder peoplevirologic failure

Identifiers

PMID31544479
PMCPMC6862950

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.