Evidence map›Paper›PMID 31544442›Full record

ArticleZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2019

[Minimally invasive treatment for osteonecrosis of the femoral head in ARCO stage

Yajie Lu, Zhen Wang, Xiao Lu, Jianxi Lu, Xiantao Chen, Dongsheng Niu, Xianfa Feng, Chengquan Zhang, Jinwei Yu, Baocang Wang

Open access · greenAbstract read
In one paragraph

Article in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. [Evaluation of multimodal analgesia in treatment of avascular necrosis of femoral head with free vascularized fibular grafting].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2020
    Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 1 country.

Yajie LuDepartment of Orthopedics, the First Affiliated Hospital of the Air Force Medical University of Chinese PLA, Xi'an Shaanxi, 710032, P.R.China.
Zhen WangDepartment of Orthopedics, the First Affiliated Hospital of the Air Force Medical University of Chinese PLA, Xi'an Shaanxi, 710032, P.R.China.wangzhen@fmmu.edu.cn.
Xiao LuShanghai Bio-lu Biomaterials Co., Ltd., Shanghai, 200000, P.R.China.
Jianxi LuShanghai Bio-lu Biomaterials Co., Ltd., Shanghai, 200000, P.R.China.lujianxi888@hotmail.com.
Xiantao ChenDepartment of Orthopedics, Luoyang Orthopedic-Trumatological Hospital of Henan Province (Henan Provincial Orthopedic Hospital), Luoyang Henan, 471000, P.R.China.
Dongsheng NiuDepartment of Orthopedics, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan Ningxia, 750021, P.R.China.
Xianfa FengDepartment of Orthopedics, Songyuan Central Hospital, Songyuan Jilin, 138000, P.R.China.
Chengquan ZhangDepartment of Orthopedics, Hanzhong Central Hospital, Hanzhong Shaanxi, 723000, P.R.China.
Jinwei YuDepartment of Orthopedics, the Second People's Hospital of Jiaozuo, Jiaozuo Henan, 454150, P.R.China.
Baocang WangDepartment of Orthopedics, the Second Hospital of Tangshan, Tangshan Hebei, 063000, P.R.China.
Xi'an Medical University · CNHanzhong Central Hospital · CNJiaozuo University · CNLuoyang Orthopedic-Traumatological Hospital of Henan Province · CNLuye Pharma (China) · CNNingxia Hui Autonomous Region Peoples Hospital · CNSecond Hospital of Tangshan · CNShanghai Genon Biological Products (China) · CNTaiyuan Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo perfect the theory system of minimally invasive treatment for osteonecrosis of the femoral head (ONFH) with β tricalcium phosphate (β-TCP) bioceramic system and evaluate the effectiveness.

methodsEighteen New Zealand white rabbits aged 7-8 months were used to establish an animal model to verify the vascularization of porous β-TCP bioceramic rods. Micro-CT based three-dimensional reconstruction and fluorescence imaging were used to display the new blood vessels at 4, 8, and 12 weeks after operation. The inserting depth, number and diameter of vessels in the encapsulated area were analyzed. Nine pig femoral specimens were randomly divided into 3 groups (

resultsAnimal experiments showed that blood vessels could grow into the encapsulated area and penetrate it at 12 weeks. The inserting depth, number and diameter of blood vessels in the encapsulated area gradually increased, and there was significant difference between different time points (

conclusionβ-TCP bioceramic system can guide the abundant blood supply of greater trochanter and femoral neck to the femoral head to promote repair; it can partly restore the mechanical properties of the femoral head and neck in the early stage, providing a new minimally invasive hip-preserving method for patients with ONFH, especially for those in early stage.

Indexed as

Femur Head NecrosisAnimalsBone TransplantationChinaFemaleFemur HeadHumansMaleRabbitsRetrospective StudiesSwineTreatment Outcomebioceramicsbiomechanicsmulticenter clinical studyOsteonecrosis of the femoral headvascularization

Identifiers

PMID31544442
PMCPMC8337643
OpenAlexW2990384028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.