Evidence map›Paper›PMID 31544296›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2020

Late-Stage Diversification of Tryptophan-Derived Biomolecules.

Hendrik Gruß, Norbert Sewald

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Peptidic Tryptophan Halogenation by a Promiscuous Flavin-Dependent Enzyme.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Nanoparticles asACS sustainable chemistry & engineering · 2024
    Article
  10. Article
  11. Article
  12. Promiscuous Enzymes for Residue-Specific Peptide and Protein Late-Stage Functionalization.Chembiochem : a European journal of chemical biology · 2023
    Review
  13. Article
  14. Enzymatic Late-Stage Halogenation of Peptides.Chembiochem : a European journal of chemical biology · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Peptide stapling by late-stage Suzuki-Miyaura cross-coupling.Beilstein journal of organic chemistry · 2022
    Article
  20. Negishi Cross-Coupling Provides Alkylated Tryptophans and Tryptophan Regioisomers.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hendrik GrußOrganische und Bioorganische Chemie, Fakultät für Chemie, Universität Bielefeld, Universitätsstraße 25, 33615, Bielefeld, Germany.
Norbert SewaldOrganische und Bioorganische Chemie, Fakultät für Chemie, Universität Bielefeld, Universitätsstraße 25, 33615, Bielefeld, Germany.ORCID http://orcid.org/0000-0002-0309-2655

Funding

Deutsche Forschungsgemeinschaft SE 609/16-1
6 · The paper itself

Abstract

Pd-mediated reactions have emerged as a powerful tool for the site-selective and bioorthogonal late-stage diversification of amino acids, peptides and related compounds. Indole moieties of tryptophan derivatives are susceptible to C

Indexed as

Amino AcidsCatalysisHalogenationPeptidesTryptophanAmino AcidsPeptidesTryptophancross-couplingenzymatic halogenationlate-stage diversificationpalladium catalysistryptophans

Identifiers

PMID31544296
PMCPMC7216954

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.