Evidence map›Paper›PMID 31544114›Full record

ArticleJournal of education and health promotion2019

Chronic exposure to organophosphate pesticides as an important challenge in promoting reproductive health: A comparative study.

Abolfazl Ghafouri-Khosrowshahi, Akram Ranjbar, Leila Mousavi, Hossein Nili-Ahmadabadi, Fatemeh Ghaffari, Hamed Zeinvand-Lorestani, Amir Nili-Ahmadabadi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of education and health promotion, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  4. Article
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  6. Review
  7. Endocrine Disrupting Agents: Toxicological Aspects on Male Reproduction.Reproductive sciences (Thousand Oaks, Calif.) · 2025
    Review
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  16. Environmental, Human and Ecotoxicological Impacts of Different Rice Cultivation Systems in Northern Thailand.International journal of environmental research and public health · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Abolfazl Ghafouri-KhosrowshahiMedicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Akram RanjbarMedicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Leila MousaviDepartment of Clinical Sciences, School of Medical Sciences, Hamadan University of Medical Sciences, Hamadan, Iran.
Hossein Nili-AhmadabadiDepartment of Internal Medicine and Gastroenterology, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran.
Fatemeh GhaffariMedicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Hamed Zeinvand-LorestaniToxicology and Poisoning Research Centre, Tehran University of Medical Sciences, Tehran, Iran.
Amir Nili-AhmadabadiMedicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Hamedan University of Medical Sciences · IRTehran University of Medical Sciences · IRYasuj University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOrganophosphate compounds (OPCs) are suspected to make changes in reproductive function by oxidant/antioxidant balance disruption in the brain, consequently impairing hypothalamic, pituitary endocrine functions, and gonadal processes. The aim of this study was to investigate the effects of occupational exposure to OPCs on the reproductive system of farm workers, in Hamadan, Iran. MATERIALS AND

methodsA comparative study was conducted in rural farmers and urban men aged 20-40 years. After sampling and analysis of semen quality parameters (such as sperm count, sperm motility, progressive sperm motility, and sperm morphology), serum butyrylcholinesterase (BChE) activity (a specific biomarker in OPCs exposure), as well as total antioxidant capacity, nitric oxide, and lipid peroxidation levels for both semen and serum samples were determined. In addition, serum samples were analyzed for reproductive hormones, including follicle-stimulating hormone, luteinizing hormone (LH), and testosterone.

resultsOur findings showed that the number of sperms (

conclusionExposure to OPCs may affect reproductive outcomes through impairing hypothalamic and/or pituitary endocrine dysfunctions and gonadal processes in farmers.

Indexed as

Farmersinfertilityorganophosphorus compoundsoxidative stresssperm quality

Identifiers

PMID31544114
PMCPMC6745885
OpenAlexW2988458073

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.