Evidence map›Paper›PMID 31543912›Full record

ArticleIranian journal of parasitology

Effect of Nitazoxanide, Artesunate Loaded Polymeric Nano Fiber and Their Combination on Experimental Cryptosporidiosis.

Enas Fakhry Abdelhamed, Eman Magdy Fawzy, Said Mahmoud Ahmed, Rabab Sayed Zalat, Hayam Elsaid Rashed

Open access · goldAbstract read
In one paragraph

Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Evaluation of potential antiparasitic effect of ZnO nanoparticles on experimental cryptosporidiosis in immunosuppressed mice.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
  2. Review
  3. Article
  4. Therapeutic potential of platelet rich plasma against experimentalJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  5. Article
  6. Frontiers in veterinary science · 2024
    Article
  7. Use of nanoparticles, a modern means of drug delivery, against cryptosporidiosis.Journal of advanced veterinary and animal research · 2023
    Review
  8. Evaluation of the therapeutic efficacy of some essential oils in experimentally immunosuppressed mice infected withJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  9. Article
  10. Article
  11. Diagnosis and control of cryptosporidiosis in farm animals.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Review
  12. Apoptotic changes in the intestinal epithelium ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Enas Fakhry AbdelhamedDepartment of Medical Parasitology, Faculty of Medicine, Zagazig University, Sharkia Governorate, Egypt.
Eman Magdy FawzyDepartment of Medical Parasitology, Faculty of Medicine, Zagazig University, Sharkia Governorate, Egypt.
Said Mahmoud AhmedDepartment of Zoology, Faculty of Science, Zagazig University, Sharkia Governorate, Egypt.
Rabab Sayed ZalatDepartment of Medical Parasitology, Theodor Bilharz Research Institute, Giza, Egypt.
Hayam Elsaid RashedDepartment of Pathology, Faculty of Medicine, Zagazig University, Sharkia Governorate, Egypt.
Zagazig University · EGTheodor Bilharz Research Institute · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsSixty Swiss Albino mice aged 6-7 wk, weighting 20-24 gm were used in Theodor Bilharz Research Institute (TBRI) Cairo, Egypt in 2017.

resultsThe novel combination between ALPN and nanazoxidehas a harmonizing effect in reducing oocyst shedding (94.4%), the mean value of the antioxidant levels in liver, intestine, kidney, and serum were the highest level (10.15, 22.4, 6.22, 14.08 respectively) resulting in the decrease of oxidative stress in tissues. Marked improvement of histopathological features was obtained.

conclusionThis combination has a promising therapeutic effect against cryptosporidiosis particularly in immunocompromised individuals considering minor toxicity.

Indexed as

ArtesunateCryptosporidiumOxidative stressPolymeric nanofiber

Identifiers

PMID31543912
PMCPMC6737357
OpenAlexW2954527122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.