Evidence map›Paper›PMID 31543247›Full record

ArticleBiological psychiatry2020

Altered Corticolimbic Control of the Nucleus Accumbens by Long-term Δ

Eun-Kyung Hwang, Carl R Lupica

Open access · greenAbstract read
In one paragraph

Article in Biological psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. ΔAddiction biology · 2023
    Article
  6. Review
  7. Targeting the Limbic System: Insights into Its Involvement in Tinnitus.International journal of molecular sciences · 2023
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Impairment of Synaptic Plasticity by Cannabis, ΔCold Spring Harbor perspectives in medicine · 2021
    Review
  13. Pharmacological Evaluation of Drugs in Animal Models of Tinnitus.Current topics in behavioral neurosciences · 2021
    Review
  14. Article
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eun-Kyung HwangElectrophysiology Research Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland.
Carl R LupicaElectrophysiology Research Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland. Electronic address: clupica@mail.nih.gov.
National Institute on Drug Abuse · US

Funding

Effect Of Drugs of Abuse On Synaptic Transmission In Nucleus AccumbensZIADA000437 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI LUPICA, CARL · 2009 to 2023
$6.8M
Molecular sites of delta-9-THC and synthetic cannabinoid actions on brain functionZIADA000487 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI LUPICA, CARL · 2009 to 2021
$6.6M
Physiology and Pharmacology of Brain Reward CircuitsZ01DA000457 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI LUPICA, CARL R · 2002 to 2008
$815k
Consequences of prolonged exposure to delta9-THC on brain functionZ01DA000487 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI LUPICA, CARL R · 2005 to 2008
$815k
Effect Of Drugs of Abuse On Synaptic Transmission In Nucleus AccumbensZ01DA000437 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI LUPICA, CARL R · 2000 to 2008
$611k
Intramural NIH HHS Z01 DA000437Intramural NIH HHS Z01 DA000457Intramural NIH HHS Z01 DA000487
6 · The paper itself

Abstract

backgroundThe decriminalization and legalization of cannabis and the expansion of availability of medical cannabis in North America have led to an increase in cannabis use and the availability of high-potency strains. Cannabis potency is determined by the concentration of Δ

methodsUsing in vitro electrophysiology and optogenetics, we examined how Δ

resultsWe found that long-term exposure to Δ

conclusionsLong-term exposure to Δ

Indexed as

CannabinoidsDronabinolAnimalsGlutamic AcidNucleus AccumbensRatsSynapsesCannabinoidsDronabinolGlutamic AcidCannabinoidCannabisGlutamateLong-term depressionMarijuanaMedicinal marijuanaSynapse

Identifiers

PMID31543247
PMCPMC7002212
OpenAlexW2964433704

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.