ArticleArchives of orthopaedic and trauma surgery2020
Do anticoagulants affect outcomes of hip fracture surgery? A cross-sectional analysis.
Article in Archives of orthopaedic and trauma surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Is hip fracture surgery safe for patients on antiplatelet drugs and is it necessary to delay surgery? A systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2020Pooled it
- Review
- Impact of three sequential orthogeriatric care models on time to surgery after hip fracture: a retrospective study.BMC geriatrics · 2025Observational
- Perioperative Management of Traditional and Direct Oral Anticoagulants in Hip Fracture Patients.Orthopedic reviews · 2024Article
- Review of perioperative outcomes and management of hip fracture patients on direct oral anticoagulants.EFORT open reviews · 2023Review
- The Effect of Warfarin Use on Postoperative Outcomes after Femoral Neck Surgery.Journal of clinical medicine · 2023Article
- Timing and safety of hip fracture surgery in patients on direct-acting oral anticoagulants.Journal of clinical orthopaedics and trauma · 2023Article
- Do anticoagulants impact the "in-house mortality" after surgical treatment of proximal femoral fractures-a multivariate analysis.International orthopaedics · 2022Article
- Early Surgical Care of Anticoagulated Hip Fracture Patients Is Feasible-A Retrospective Chart Review of Hip Fracture Patients Treated with Hip Arthroplasty within 24 Hours.Journal of clinical medicine · 2022Article
- Early versus delayed surgery for hip fragility fractures in patients treated with direct oral anticoagulants.Archives of orthopaedic and trauma surgery · 2022Article
- Article
- [Risk factors affecting mortality in patients with hip fractures at a regional trauma center].Zeitschrift fur Gerontologie und Geriatrie · 2021Article
- Should patients treated with oral anti-coagulants be operated on within 48 h of hip fracture?Journal of thrombosis and thrombolysis · 2021Article
- Direct oral anticoagulants (DOACs) and neck of femur fractures: Standardising the perioperative management and time to surgery.Journal of clinical orthopaedics and trauma · 2021Article
- Do direct oral anticoagulants (DOACs) cause delayed surgery, longer length of hospital stay, and poorer outcome for hip fracture patients?European geriatric medicine · 2020Article
- Direct Oral Anticoagulants and Timing of Hip Fracture Surgery.Journal of clinical medicine · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe management of patients with a hip fracture is affected by the use of oral anticoagulants. A cross-sectional analysis was undertaken to investigate health outcome differences in those anticoagulated compared to those not anticoagulated.
methodsPatients aged 50 years and over presenting to a large university hospital with hip fractures were identified from the service registry. Patient characteristics and health outcomes between those not anticoagulated were compared with those anticoagulated (warfarin and direct oral anticoagulants, DOAC).
results200/2307 (9%) patients were anticoagulated. 84% were on warfarin, and the rest a DOAC. Compared to those anticoagulated, there was a higher prevalence of dementia (25% vs. 18%, p = 0.02) and a lower prevalence of cardiovascular disease (54% vs. 78%, p < 0.01), atrial fibrillation (10% vs. 82%, p < 0.01), and polypharmacy (55% vs. 76%, p < 0.01). Renal function was lower in the anticoagulated group. Time to operation for those not anticoagulated and anticoagulated was a median (IQR) of 25 (15) and 27 (18) hours. There was no difference in blood transfusion and hospital mortality. Postoperative complications were similar except a higher rate of renal failure (14% vs. 19%, p = 0.04) and heart failure (1% vs. 5%, p < 0.01), and a longer length of stay [median (IQR): 14 (10) vs. 16 (12) days] in the anticoagulated group. This was no longer significant after adjustment of confounders.
conclusionThere was no statistically significant difference in health outcomes between those anticoagulated and those not after adjusting for patient characteristics. It was feasible to avoid significant delay in hip fracture surgery in those anticoagulated.
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