Evidence map›Paper›PMID 31542754›Full record

ArticleBMJ open2019

Clinicopathological risk factors for gastric cancer: a retrospective cohort study in China.

Kongwang Hu, Shuaili Wang, Zikun Wang, Longlong Li, Zhiguo Huang, Weiqiang Yu, Zhongxue Chen, Qing-Fa Wu

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Targeting PI3K/AKT/mTOR and MAPK Signaling Pathways in Gastric Cancer.International journal of molecular sciences · 2024
    Review
  8. Article
  9. Significance of Serum Apelin Levels as a Biomarker for Gastric Cancer Diagnosis.Asian Pacific journal of cancer prevention : APJCP · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kongwang HuDepartment of General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Shuaili WangSchool of Life Sciences, University of Science and Technology of China, Hefei, China.
Zikun WangDepartment of Epidemiology and Biostatistics, School of Public Health, Indiana University Bloomington, Bloomington, Indiana, USA.
Longlong LiDepartment of General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhiguo HuangDepartment of General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Weiqiang YuSchool of Life Sciences, University of Science and Technology of China, Hefei, China.
Zhongxue ChenDepartment of Epidemiology and Biostatistics, School of Public Health, Indiana University Bloomington, Bloomington, Indiana, USA zc3@indiana.edu wuqf@ustc.edu.cn.ORCID 0000-0003-2537-7843
Qing-Fa WuSchool of Life Sciences, University of Science and Technology of China, Hefei, China zc3@indiana.edu wuqf@ustc.edu.cn.
Anhui Medical University · CNUniversity of Science and Technology of China · CNIndiana University Bloomington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the potential clinicopathological factors affecting the prognosis of patients with gastric cancer after surgical treatment in China.

methodsBetween 1 January 2001 and 31 December 2012, a total of 716 patients aged 22-84 years with gastric cancer were enrolled in the study. Survival analysis techniques including log rank test and Cox proportional hazard regression model were applied to evaluate the prognostic significance of clinicopathological characteristics in terms of survival time.

resultsOf the 24 demographic and pathological variables collected in the data, 16 prognostic factors of gastric cancer were found to have statistically significant influences on survival time from the unadjusted analyses. The adjusted analysis furtherly revealed that age, age square, lymph node metastasis rate group, tumour size group, surgical type II, number of cancer nodules, invasion depth group and the interaction between surgical type II and tumour size group were important prognosis and clinicopathological factors for gastric cancer in Chinese.

conclusionOur study with relatively large sample size and many potential risk factors enable us to identify independent risk factors associated with the prognosis of gastric cancer. Findings from the current study can be used to assist clinical decision-making, and serve as a benchmark for the planning of future prognosis and therapy for patients with gastric carcinoma.

Indexed as

AdultAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsStomach NeoplasmsSurvival AnalysisSurvival RateYoung Adultclinical stageclinicopathologic risk factorsgastric carcinomalymph node metastasis rate

Identifiers

PMID31542754
PMCPMC6756371
OpenAlexW2974351489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.