Trial reportBMJ open2019
Evaluating the effectiveness of the NHS Health Check programme in South England: a quasi-randomised controlled trial.
Trial report in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Effectiveness and cost-effectiveness of general health checks in adults: A systematic review.BMC public health · 2026Pooled it
- Strategies to improve smoking cessation rates in primary care.The Cochrane database of systematic reviews · 2021Pooled it
- Evaluating the effectiveness of the cardiovascular assessment screening program with nurse practitioners and patients: results of a cluster randomised controlled trial.BMC primary care · 2024Trial
- Effectiveness of check-up 35 for detecting targeted diseases in Germany.BMC primary care · 2026Article
- Ethnic differences in the burden of cardiovascular disease risk factors among adult residents of London: the TOGETHER study.BMC medicine · 2026Article
- Prevalence of Cardiovascular Risk Factors Among Adults in the European Union: A Systematic Review with Meta-Analysis.Journal of clinical medicine · 2025Review
- Assessment of cardiovascular risk factors and effect of lifestyle in individuals without cardiovascular disease, diabetes or chronic kidney disease.Scientific reports · 2025Article
- From Atherosclerotic Plaque to Myocardial Infarction-The Leading Cause of Coronary Artery Occlusion.International journal of molecular sciences · 2024Review
- The impact of lifestyle, measured with the HLPCQ questionnaire on the prevalence of metabolic syndrome in Poland: a multicenter study.Scientific reports · 2024Article
- Observational
- Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002-2017).Diagnostics (Basel, Switzerland) · 2022Article
- NHS Health Check programme: a rapid review update.BMJ open · 2022Review
- NHS Health Checks: an observational study of equity and outcomes 2009-2017.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate uptake, risk factor detection and management from the National Health Service (NHS) Health Check (HC).
designThis is a quasi-randomised controlled trial where participants were allocated to five cohorts based on birth year. Four cohorts were invited for an NHS HC between April 2011 and March 2015.
setting151 general practices in Hampshire, England, UK.
participants366 005 participants born 1 April 1940-31 March 1976 eligible for an NHS HC.
interventionNHS HC invitation.
main outcome measuresHC attendance and absolute percentage changes and ORs of (1) detecting cardiovascular disease (CVD) 10-year risk >10% and >20%, smokers, and total cholesterol (TC) >5.5 mmol/L and >7.5 mmol/L; (2) diagnosing hypertension, type 2 diabetes mellitus, chronic kidney disease (CKD) and atrial fibrillation (AF); and (3) new interventions with statins, antihypertensives, antiglycaemics and nicotine replacement therapy (NRT).
resultsHC attendance rose from 12% to 30% between 2011/2012 and 2014/2015 (p<0.001). HC invitation increased detection of CVD risk >10% (2.0%-3.6, p<0.001) and >20% (0.1%-0.6%, p<0.001-0.392), TC >5.5 mmol/L (4.1%-7.0%, p<0.001) and >7.5 mmol/L (0.3%-0.4% p<0.001), hypertension (0.3%-0.6%, p<0.001-0.003), and interventions with statins (0.2%-0.9%, p<0.001-0.017) and antihypertensives (0.1%-0.6%, p<0.001-0.205). There were no consistent differences in detection of smokers, NRT, or diabetes, AF or CKD. Multivariate analyses showed associations between HC invitation and detecting CVD risk >10% (OR 8.01, 95% CI 7.34 to 8.73) and >20% (5.86, 4.83 to 7.10), TC >5.5 mmol/L (3.72, 3.57 to 3.89) and >7.5 mmol/L (2.89, 2.46 to 3.38), and diagnoses of hypertension (1.33, 1.20 to 1.47) and diabetes (1.34, 1.12 to 1.61). OR of CVD risk >10% plus statin and >20% plus statin, respectively, was 2.90 (2.36 to 3.57) and 2.60 (1.92 to 3.52), and for hypertension plus antihypertensive was 1.33 (1.18 to 1.50). There were no associations with AF, CKD, antiglycaemics or NRT. Detection of several risk factors varied inversely by deprivation.
conclusionsHC invitation increased detection of cardiovascular risk factors, but corresponding increases in evidence-based interventions were modest.
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