Evidence map›Paper›PMID 31542740›Full record

Observational studyBMJ open2019

Observational retrospective study of the association of initial healthcare provider for new-onset low back pain with early and long-term opioid use.

Lewis E Kazis, Omid Ameli, James Rothendler, Brigid Garrity, Howard Cabral, Christine McDonough, Kathleen Carey, Michael Stein, Darshak Sanghavi, David Elton and 2 more

Erratum issuedAbstract readComparative StudyObservational Study
In one paragraph

Observational study in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 77 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
    2020
5 · Who and what money

Authors and funding

12 authors.

Lewis E KazisDepartment of Health Law, Policy and Management, Boston University School of Public Health, Boston, Massachusetts, USA lek@bu.edu.
Omid AmeliDepartment of Health Law, Policy and Management, Boston University School of Public Health, Boston, Massachusetts, USA.
James RothendlerDepartment of Health Law, Policy and Management, Boston University School of Public Health, Boston, Massachusetts, USA.
Brigid GarrityDepartment of Health Law, Policy and Management, Boston University School of Public Health, Boston, Massachusetts, USA.
Howard CabralDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
Christine McDonoughUniversity of Pittsburgh School of Health and Rehabilitation Sciences, Pittsburgh, Pennsylvania, USA.
Kathleen CareyDepartment of Health Law, Policy and Management, Boston University School of Public Health, Boston, Massachusetts, USA.
Michael SteinDepartment of Health Law, Policy and Management, Boston University School of Public Health, Boston, Massachusetts, USA.
Darshak SanghaviOptumLabs, Cambridge, Massachusetts, USA.
David EltonOptumHealth, Eden Prairie, Minnesota, USA.
Julie FritzPhysical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, USA.
Robert SaperBoston University Medical Campus, Boston, Massachusetts, USA.

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
NCATS NIH HHS UL1 TR002538
6 · The paper itself

Abstract

objectiveThis study examined the association of initial provider treatment with early and long-term opioid use in a national sample of patients with new-onset low back pain (LBP).

designA retrospective cohort study of patients with new-onset LBP from 2008 to 2013.

settingThe study evaluated outpatient and inpatient claims from patient visits, pharmacy claims and inpatient and outpatient procedures with initial providers seen for new-onset LBP.

participants216 504 individuals aged 18 years or older across the USA who were diagnosed with new-onset LBP and were opioid-naïve were included. Participants had commercial or Medicare Advantage insurance. EXPOSURES: The primary independent variable is type of initial healthcare provider including physicians and conservative therapists (physical therapists, chiropractors, acupuncturists).

main outcome measuresShort-term opioid use (within 30 days of the index visit) following new LBP visit and long-term opioid use (starting within 60 days of the index date and either 120 or more days' supply of opioids over 12 months, or 90 days or more supply of opioids and 10 or more opioid prescriptions over 12 months).

resultsShort-term use of opioids was 22%. Patients who received initial treatment from chiropractors or physical therapists had decreased odds of short-term and long-term opioid use compared with those who received initial treatment from primary care physicians (PCPs) (adjusted OR (AOR) (95% CI) 0.10 (0.09 to 0.10) and 0.15 (0.13 to 0.17), respectively). Compared with PCP visits, initial chiropractic and physical therapy also were associated with decreased odds of long-term opioid use in a propensity score matched sample (AOR (95% CI) 0.21 (0.16 to 0.27) and 0.29 (0.12 to 0.69), respectively).

conclusionsInitial visits to chiropractors or physical therapists is associated with substantially decreased early and long-term use of opioids. Incentivising use of conservative therapists may be a strategy to reduce risks of early and long-term opioid use.

Indexed as

AdolescentAdultAgedAged, 80 and overAnalgesics, OpioidDrug PrescriptionsFemaleHumansLogistic ModelsLow Back PainMaleMedicareMiddle AgedOpioid-Related DisordersPatient Acceptance of Health CarePhysical Therapy ModalitiesAnalgesics, OpioidBack painopioidOpioid usePAIN MANAGEMENT

Identifiers

PMID31542740
PMCPMC6756340

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.