Evidence map›Paper›PMID 31541410›Full record

SynthesisSports medicine (Auckland, N.Z.)2020

Exercise as Medicine for Mental and Substance Use Disorders: A Meta-review of the Benefits for Neuropsychiatric and Cognitive Outcomes.

Garcia Ashdown-Franks, Joseph Firth, Rebekah Carney, Andre F Carvalho, Mats Hallgren, Ai Koyanagi, Simon Rosenbaum, Felipe B Schuch, Lee Smith, Marco Solmi and 2 more

Registry-linked trialOpen access · bronzeAbstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05061225 (The Efficacy of a Facebook-delivered Physical Activity Counselling Intervention on Mental Health in Firefighters), which is not on this map. Cited by 172 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed, 13 pooled it
45.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05061225 naunknown statusnot on this mapstarted 2021, after this paper: background citation

The Efficacy of a Facebook-delivered Physical Activity Counselling Intervention on Mental Health in Firefighters: a Randomized Controlled Trial

TypeinterventionalSponsorKU LeuvenRan2021 to 2022Enrolled60ConditionsPTSD, Stress, Psychological, Depressive Symptoms, Anxiety Disorders and SymptomsArmsPhysical activity counselling
3 · Its place in the literature

Who cites it

172 citing papers in PubMed, 13 syntheses or guidelines pooled it, 419 citations in OpenAlex.

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  17. Predictors of adherence to exercise interventions in people with schizophrenia.European archives of psychiatry and clinical neuroscience · 2024
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112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 8 countries.

Garcia Ashdown-FranksSouth London and Maudsley NHS Foundation Trust, Denmark Hill, London, SE5 8AZ, UK.ORCID http://orcid.org/0000-0002-5032-0171
Joseph FirthNICM Health Research Institute, Western Sydney University, Westmead, Australia.
Rebekah CarneyYouth Mental Health Research Unit, Greater Manchester Mental Health NHS Foundation Trust, Manchester, UK.
Andre F CarvalhoDepartment of Psychiatry, University of Toronto and Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.
Mats HallgrenUnit of Epidemiology of Psychiatric Conditions, Substance Use and Social Environment (EPiCS), Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Ai KoyanagiResearch and Development Unit, Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu, Dr Antoni Pujadas, 42, Sant Boi de Llobregat, 08830, Barcelona, Spain.
Simon RosenbaumSchool of Psychiatry UNSW, Sydney, Australia.
Felipe B SchuchDepartment of Methods and Sports Techniques, Universidade Federal de Santa Maria, Santa Maria, Brazil.
Lee SmithThe Cambridge Centre for Sport and Exercise Sciences, Anglia Ruskin University, Cambridge, UK.
Marco SolmiNeurosciences Department, University of Padova, Padua, Italy.
Davy VancampfortDepartment of Rehabilitation Sciences, KU Leuven, Louvain, Belgium.
Brendon StubbsSouth London and Maudsley NHS Foundation Trust, Denmark Hill, London, SE5 8AZ, UK. brendon.stubbs@kcl.ac.uk.
King's College London · GBAnglia Ruskin University · GBBlack Dog Institute · AUCentre for Addiction and Mental Health · CAGreater Manchester Mental Health NHS Foundation Trust · GBKarolinska Institutet · SEKU Leuven · BEParc Sanitari Sant Joan de Déu · ESThe University of Melbourne · AUUniversidade Federal de Santa Maria · BRUniversity of Padua · IT

Funding

Department of Health ICA-CL-2017-03-001Health Education England and NIHR Integrated Clinical Academic (ICA) Programme ICA-CL-2017-03-001
6 · The paper itself

Abstract

backgroundExercise may improve neuropsychiatric and cognitive symptoms in people with mental disorders, but the totality of the evidence is unclear. We conducted a meta-review of exercise in (1) serious mental illness (schizophrenia spectrum, bipolar disorder and major depression (MDD)); (2) anxiety and stress disorders; (3) alcohol and substance use disorders; (4) eating disorders (anorexia nervosa bulimia nervosa, binge eating disorders, and (5) other mental disorders (including ADHD, pre/post-natal depression).

methodsSystematic searches of major databases from inception until 1/10/2018 were undertaken to identify meta-analyses of randomised controlled trials (RCTs) of exercise in people with clinically diagnosed mental disorders. In the absence of available meta-analyses for a mental disorder, we identified systematic reviews of exercise interventions in people with elevated mental health symptoms that included non-RCTs. Meta-analysis quality was assessed with the AMSTAR/+.

resultsOverall, we identified 27 systematic reviews (including 16 meta-analyses representing 152 RCTs). Among those with MDD, we found consistent evidence (meta-analyses = 8) that exercise reduced depression in children, adults and older adults. Evidence also indicates that exercise was more effective than control conditions in reducing anxiety symptoms (meta-analyses = 3), and as an adjunctive treatment for reducing positive and negative symptoms of schizophrenia (meta-analyses = 2). Regarding neurocognitive effects, exercise improved global cognition in schizophrenia (meta-analyses = 1), children with ADHD (meta-analyses = 1), but not in MDD (meta-analyses = 1). Among those with elevated symptoms, positive mental health benefits were observed for exercise in people with pre/post-natal depression, anorexia nervosa/bulimia nervosa, binge eating disorder, post-traumatic stress disorder and alcohol use disorders/substance use disorders. Adverse events were sparsely reported.

conclusionOur panoramic meta-overview suggests that exercise can be an effective adjunctive treatment for improving symptoms across a broad range of mental disorders.

Indexed as

Exercise TherapyFeeding and Eating DisordersHumansMental DisordersRandomized Controlled Trials as TopicSubstance-Related DisordersSystematic Reviews as Topic

Identifiers

PMID31541410
OpenAlexW2972381227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.