Evidence map›Paper›PMID 31541396›Full record

ArticleJournal of biomolecular NMR2019

Improved strategy for isoleucine

Rustam Ali, Lindsay D Clark, Jacob A Zahm, Andrew Lemoff, Karthik Ramesh, Daniel M Rosenbaum, Michael K Rosen

Open access · hybridAbstract read
In one paragraph

Article in Journal of biomolecular NMR, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. A ProbioticToxins · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rustam AliDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. rustam.ali@utsouthwestern.edu.
Lindsay D ClarkDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.ORCID http://orcid.org/0000-0001-6879-6883
Jacob A ZahmDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Andrew LemoffDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Karthik RameshDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Daniel M RosenbaumDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Michael K RosenDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. michael.rosen@utsouthwestern.edu.ORCID http://orcid.org/0000-0002-0775-7917
The University of Texas Southwestern Medical Center · USHoward Hughes Medical Institute · USHarvard University · USSouthwestern Medical Center · US

Funding

STRUCTURAL STUDY OF RHO-GTPASE REGULATORS AND EFFECTORSR01GM056322 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI ROSEN, MICHAEL K · 1997 to 2019
$5.7M
Cell Organization Through Phase Separation: Mechanisms, Functions and DiseaseR35GM141736 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI ROSEN, MICHAEL K · 2021 to 2025
$1.8M
Acquisition of upgrades for 800 MHz NMR consoleS10OD018027 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2014 to 2014
$376k
600MHz Varian VNMRS Console UpgradeS10RR026461 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI ROSEN, MICHAEL K · 2010 to 2010
$254k
American Heart Association 16POST27260081American Heart Association 16PRE27200004Directorate for Biological Sciences 1000136529NCRR NIH HHS 1S10OD018027-01NCRR NIH HHS 1S10RR26461-1NCRR NIH HHS S10 RR026461NIGMS NIH HHS R01 GM056322NIGMS NIH HHS R01-GM56322NIGMS NIH HHS R35 GM141736NIH HHS S10 OD018027Welch Foundation I-1544Welch Foundation I-1770
6 · The paper itself

Abstract

Site specific methyl labeling combined with methyl TROSY offers a powerful NMR approach to study structure and dynamics of proteins and protein complexes of high molecular weight. Robust and cost-effective methods have been developed for site specific protein

Indexed as

ActinsCarbon IsotopesDeuteriumFungal ProteinsIsoleucineIsotope LabelingNuclear Magnetic Resonance, BiomolecularPichiaReceptors, G-Protein-CoupledActinsCarbon IsotopesDeuteriumFungal ProteinsIsoleucineReceptors, G-Protein-Coupled13C methyl labelingDeuterationEukaryotic protein expressionMethyl TROSYPichia pastoris expression

Identifiers

PMID31541396
PMCPMC6875547
OpenAlexW2973469784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.