ArticleSocial psychiatry and psychiatric epidemiology2020
Four-year course of quality of life and obsessive-compulsive disorder.
Article in Social psychiatry and psychiatric epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Anxiety, Depression and Quality of Life-A Systematic Review of Evidence from Longitudinal Observational Studies.International journal of environmental research and public health · 2021Pooled it
- Comparing Different Montages of Transcranial Direct Current Stimulation in Treating Treatment-Resistant Obsessive Compulsive Disorder: A Randomized, Single-Blind Clinical Trial.Medicina (Kaunas, Lithuania) · 2025Trial
- Inference-Based Cognitive Behavioral Therapy versus Cognitive Behavioral Therapy for Obsessive-Compulsive Disorder: A Multisite Randomized Controlled Non-Inferiority Trial.Psychotherapy and psychosomatics · 2024Trial
- Associations among mediodorsal thalamic-ventrolateral prefrontal cortical white matter fiber dispersion and OCD-related incompleteness.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Early life adversity, inhibitory control, and behavioral dysregulation among individuals with OCD.Psychiatry research · 2026Article
- Latent profile analysis of obsessive-compulsive symptoms and its relationship with the Big Five Personality Inventory among college students.BMC psychology · 2026Article
- Brief intervention, lasting impact: One-year outcomes of the Bergen 4-day treatment for OCD in Germany.PloS one · 2026Article
- Elevated cortisol/DHEA ratio mediates the association between symptom severity and working memory impairment in drug-naive, first-episode OCD.Frontiers in psychiatry · 2026Article
- Beyond the Numbers: Quantitative and qualitative analysis of quality of life after deep brain stimulation for OCD.PloS one · 2026Article
- Increased Neuroplasticity in Frontal Cortex to Reduce Compulsive Behavior: A Preclinical tDCS Study in Male Rats.Molecular neurobiology · 2025Article
- Family Accommodation of OCD and Anxiety Symptoms Across the Lifespan.The Behavior therapist · 2025Article
- Psychopathological Implications of Behavioral Patterns in Obsessive-Compulsive Rituals: A Hierarchical Analysis.Brain sciences · 2025Article
- Three cases with chronic obsessive compulsive disorder report gains in wellbeing and function following rituximab treatment.Molecular psychiatry · 2025Article
- The bidirectional relationship between severity of obsessive-compulsive symptoms and lifestyle factors in patients with obsessive-compulsive disorder: a contemporaneous and prospective analysis.Frontiers in psychiatry · 2025Article
- Gender differences in the relationship between obsessive-compulsive symptoms and suicide risk among psychiatric outpatient adolescents: the role of depressive symptoms, anxiety symptoms, and sleep disturbances.Frontiers in public health · 2025Article
- Examining relationships among NODDI indices of white matter structure in prefrontal cortical-thalamic-striatal circuitry and OCD symptomatology.Translational psychiatry · 2024Article
- Patient Perceptions of Illness Causes and Treatment Preferences for Obsessive-Compulsive Disorder: A Mixed-Methods Study.Culture, medicine and psychiatry · 2024Article
- Willingness to experience unpleasant thoughts, emotions, and bodily sensations at admission does not predict treatment outcome in inpatients with obsessive-compulsive disorder.Discover mental health · 2024Article
- Functional and structural MRI based obsessive-compulsive disorder diagnosis using machine learning methods.BMC psychiatry · 2023Article
- Dopamine Transporter Knockout Rats Show Impaired Wellbeing in a Multimodal Severity Assessment Approach.Frontiers in behavioral neuroscience · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePatients with obsessive compulsive disorder (OCD) have high disease burden. It is important to restore quality of life (QoL) in treatment, so that patients become able to live a fulfilling life. Little is known about the longitudinal course of QoL in patients with OCD, its association with remission from OCD, and about factors that contribute to an unfavourable course of QoL in remitting patients.
methodsStudy on the 4-year course of QoL of patients with chronic (n = 144), intermittent (n = 22), and remitting OCD (n = 73) using longitudinal data of the Netherlands Obsessive Compulsive Disorder Association (NOCDA; complete data: n = 239; imputed data n = 382). The EuroQol five-dimensional questionnaire (EQ-5D) utility score was used to assess QoL. In patients with remitting OCD, we examined patient characteristics that contributed to an unfavourable course of QoL, including sociodemographics, OCD characteristics, psychiatric comorbidity, and personality traits.
resultsCourse of QoL was associated with course of OCD. QoL improved in those who remitted from OCD; however, even in these patients, QoL remained significantly below the population norms. The correlation between QoL and severity of OCD was only moderate: r = - 0.40 indicating that other factors besides OCD severity contribute to QoL. In remitters, more severe anxiety and depression symptoms were related to a lower QoL. Results were similar in complete and imputed data sets.
conclusionsRemission from OCD is associated with improvement of QoL, but comorbid anxiety and depression symptoms hamper the improvement of QoL. QoL could be improved by reducing OCD symptoms in patients with OCD and by treating comorbid anxiety and depression symptoms in remitting patients.
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