Evidence map›Paper›PMID 31541224›Full record

ReviewNature reviews. Drug discovery2019

Next-generation regulatory T cell therapy.

Leonardo M R Ferreira, Yannick D Muller, Jeffrey A Bluestone, Qizhi Tang

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Drug discovery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 281 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
281citing papers in PubMed, 2 pooled it
20.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

281 citing papers in PubMed, 2 syntheses or guidelines pooled it, 462 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Selective decrease of donor-reactive TScience translational medicine · 2022
    Trial
  4. Article
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  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
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  14. Article
  15. GPSM1 restricts CD73Nature communications · 2026
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article

221 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Leonardo M R FerreiraDepartment of Surgery, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-2491-9866
Yannick D MullerDepartment of Surgery, University of California, San Francisco, San Francisco, CA, USA.
Jeffrey A BluestoneDiabetes Center, University of California, San Francisco, San Francisco, CA, USA. jeff.bluestone@ucsf.edu.ORCID http://orcid.org/0000-0001-8793-7848
Qizhi TangDepartment of Surgery, University of California, San Francisco, San Francisco, CA, USA. qizhi.tang@ucsf.edu.ORCID http://orcid.org/0000-0001-7313-3574
University of California, San Francisco · US

Funding

Designer Tregs for restoring tolerance in patients with type 1 diabetesUC4DK116264 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BLUESTONE, JEFFREY A, LIM, WENDELL A · 2017 to 2017
$3.4M
NIDDK NIH HHS UC4 DK116264
6 · The paper itself

Abstract

Regulatory T cells (T

Indexed as

AnimalsAutoimmune DiseasesCell- and Tissue-Based TherapyGraft RejectionHumansNeoplasmsT-Lymphocytes, Regulatory

Identifiers

PMID31541224
PMCPMC7773144
OpenAlexW2974877234

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.