Evidence map›Paper›PMID 31541190›Full record

ArticleScientific reports2019

Light-induced changes of the subretinal space of the temporal retina observed via optical coherence tomography.

Alina Messner, René M Werkmeister, Gerald Seidel, Hannes Stegmann, Leopold Schmetterer, Valentin Aranha Dos Santos

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Subretinal Aspects of the Optoretinographic Response.Investigative ophthalmology & visual science · 2026
    Article
  3. Subretinal aspects of the optoretinographic response.bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. The outdoor environment affects retinal and choroidal thickness.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alina MessnerCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090, Vienna, Austria.
René M WerkmeisterCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090, Vienna, Austria.
Gerald SeidelDepartment of Ophthalmology, Medical University of Graz, 8036, Graz, Austria.
Hannes StegmannCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090, Vienna, Austria.
Leopold SchmettererCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090, Vienna, Austria.
Valentin Aranha Dos SantosCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090, Vienna, Austria. valentin.aranhadossantos@meduniwien.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoreceptor function is impaired in many retinal diseases like age-related macular degeneration. Currently, assessment of the photoreceptor function for the early diagnosis and monitoring of these diseases is either subjective, as in visual field testing, requires contact with the eye, like in electroretinography, or relies on research prototypes with acquisition speeds unattained by conventional imaging systems. We developed an objective, noncontact method to monitor photoreceptor function using a standard optical coherence tomography system. This method can be used with various white light sources for stimulation. The technique was applied in five volunteers and detected a decrease of volume of the subretinal space associated with light adaptation processes of the retina.

Indexed as

AdultFemaleHealthy VolunteersHumansImage Interpretation, Computer-AssistedLightMaleRetinaTomography, Optical Coherence

Identifiers

PMID31541190
PMCPMC6754376

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.