Evidence map›Paper›PMID 31541182›Full record

ArticleCellular & molecular immunology2021

DAPK1 (death associated protein kinase 1) mediates mTORC1 activation and antiviral activities in CD8

Zhengping Wei, Pingfei Li, Ran He, Huicheng Liu, Na Liu, Yu Xia, Guoyu Bi, Qiuyang Du, Minghui Xia, Lei Pei and 10 more

Open access · bronzeAbstract read
In one paragraph

Article in Cellular & molecular immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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  10. Transcription factor EB coordinates environmental cues to regulate T regulatory cells' mitochondrial fitness and function.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 2 countries.

Zhengping Wei *Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Pingfei Li *Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Ran HeDepartment of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Huicheng LiuDepartment of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Na LiuDepartment of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Yu XiaDepartment of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Guoyu BiDepartment of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Qiuyang DuDepartment of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Minghui XiaDepartment of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Lei PeiInstitute of Brain Research, Huazhong University of Science and Technology, Wuhan, 430030, China.
Jing WangDepartment of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Guihua WangDepartment of Surgery, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, China.
Zhao-Hui TangDepartment of Surgery, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, China.
Xiang ChengLaboratory of Cardiovascular Immunology, Institute of Cardiology, Union Hospital, Tongji Medical College, HUST, Wuhan, 430030, China.
Huabin LiDepartment of Otolaryngology, Head and Neck Surgery, Affiliated Eye-Ear-Nose and Throat Hospital, Fudan University, Shanghai, 200433, China.
Zhuoya LiDepartment of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Lilin YeInstitute of Immunology, Medical School, Third Military Medical University, Chongqing, 400038, China.
Arian LaurenceDepartment of Haematology, University College London Hospitals NHS Trust, London, UK.
Youming LuInstitute of Brain Research, Huazhong University of Science and Technology, Wuhan, 430030, China.
Xiang-Ping YangDepartment of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. yangxp@hust.edu.cn.
Huazhong University of Science and Technology · CNArmy Medical University · CNFudan University · CNUnion Hospital · CNUniversity College London Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanistic target of rapamycin complex 1 (mTORC1) regulates CD8

Indexed as

Lymphocyte ActivationAnimalsAntiviral AgentsArenaviridae InfectionsCD8-Positive T-LymphocytesCell DifferentiationDeath-Associated Protein KinasesLymphocytic choriomeningitis virusMechanistic Target of Rapamycin Complex 1MiceMice, Inbred C57BLMice, KnockoutPhosphatidylinositol 3-KinasesPhosphorylationSignal TransductionTOR Serine-Threonine KinasesAntiviral AgentsDapk1 protein, mouseDeath-Associated Protein KinasesMechanistic Target of Rapamycin Complex 1mTOR protein, mousePhosphatidylinositol 3-KinasesTOR Serine-Threonine Kinasesantiviral functionmTORC1; CD8+ T cells

Identifiers

PMID31541182
PMCPMC7852660
OpenAlexW2973293314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.