Evidence map›Paper›PMID 31541159›Full record

ArticleScientific reports2019

Formation of Pseudomonas aeruginosa Biofilms in Full-thickness Scald Burn Wounds in Rats.

Kenneth S Brandenburg, Alan J Weaver, S L Rajasekhar Karna, Tao You, Ping Chen, Shaina Van Stryk, Liwu Qian, Uzziel Pineda, Johnathan J Abercrombie, Kai P Leung

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Review
  3. UnderstandingMicroorganisms · 2026
    Review
  4. Lower respiratory tract microbiota characteristics in patients withFrontiers in cellular and infection microbiology · 2026
    Article
  5. Review
  6. International journal of molecular sciences · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Advances in the Sensing and Treatment of Wound Biofilms.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022
    Review
  16. Advances in the Sensing and Treatment of Wound Biofilms.Angewandte Chemie (International ed. in English) · 2022
    Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kenneth S BrandenburgDental and Craniofacial Trauma Research and Tissue Regeneration Department, United States Army Institute of Surgical Research, 3650 Chambers Pass, Bldg 3610, JBSA Fort Sam, Houston, Texas, 78234, USA.
Alan J WeaverDental and Craniofacial Trauma Research and Tissue Regeneration Department, United States Army Institute of Surgical Research, 3650 Chambers Pass, Bldg 3610, JBSA Fort Sam, Houston, Texas, 78234, USA.
S L Rajasekhar KarnaDental and Craniofacial Trauma Research and Tissue Regeneration Department, United States Army Institute of Surgical Research, 3650 Chambers Pass, Bldg 3610, JBSA Fort Sam, Houston, Texas, 78234, USA.
Tao YouDental and Craniofacial Trauma Research and Tissue Regeneration Department, United States Army Institute of Surgical Research, 3650 Chambers Pass, Bldg 3610, JBSA Fort Sam, Houston, Texas, 78234, USA.
Ping ChenDental and Craniofacial Trauma Research and Tissue Regeneration Department, United States Army Institute of Surgical Research, 3650 Chambers Pass, Bldg 3610, JBSA Fort Sam, Houston, Texas, 78234, USA.
Shaina Van StrykDental and Craniofacial Trauma Research and Tissue Regeneration Department, United States Army Institute of Surgical Research, 3650 Chambers Pass, Bldg 3610, JBSA Fort Sam, Houston, Texas, 78234, USA.
Liwu QianDental and Craniofacial Trauma Research and Tissue Regeneration Department, United States Army Institute of Surgical Research, 3650 Chambers Pass, Bldg 3610, JBSA Fort Sam, Houston, Texas, 78234, USA.
Uzziel PinedaDental and Craniofacial Trauma Research and Tissue Regeneration Department, United States Army Institute of Surgical Research, 3650 Chambers Pass, Bldg 3610, JBSA Fort Sam, Houston, Texas, 78234, USA.
Johnathan J AbercrombieDental and Craniofacial Trauma Research and Tissue Regeneration Department, United States Army Institute of Surgical Research, 3650 Chambers Pass, Bldg 3610, JBSA Fort Sam, Houston, Texas, 78234, USA.
Kai P LeungDental and Craniofacial Trauma Research and Tissue Regeneration Department, United States Army Institute of Surgical Research, 3650 Chambers Pass, Bldg 3610, JBSA Fort Sam, Houston, Texas, 78234, USA. kai.p.leung.civ@mail.mil.
United States Army Institute of Surgical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using Sprague-Dawley rats (350-450 g; n = 61) and the recently updated Walker-Mason rat scald burn model, we demonstrated that Pseudomonas aeruginosa readily formed biofilms within full-thickness burn wounds. Following the burn, wounds were surface-inoculated with P. aeruginosa in phosphate-buffered saline (PBS), while sterile PBS was used for controls. On post-burn days 1, 3, 7, and 11, animals were euthanized and samples collected for quantitative bacteriology, bacterial gene expression, complete blood cell counts, histology, and myeloperoxidase activity. Robust biofilm infections developed in the full-thickness burn wounds inoculated with 1 × 10

Indexed as

AnimalsBiofilmsBurnsDisease Models, AnimalMaleNeutrophilsPseudomonas aeruginosaPseudomonas InfectionsRatsRats, Sprague-DawleySoft Tissue InjuriesWound InfectionWounds and Injuries

Identifiers

PMID31541159
PMCPMC6754504
OpenAlexW2974040984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.