Evidence map›Paper›PMID 31540982›Full record

ArticleApplied and environmental microbiology2019

Loci Encoding Compounds Potentially Active against Drug-Resistant Pathogens amidst a Decreasing Pool of Novel Antibiotics.

Joseph Basalla, Payel Chatterjee, Elizabeth Burgess, Mahnur Khan, Emily Verbrugge, Daniel D Wiegmann, John J LiPuma, Hans Wildschutte

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Joseph BasallaDepartment of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA.
Payel ChatterjeeDepartment of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA.
Elizabeth BurgessDepartment of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA.
Mahnur KhanDepartment of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA.
Emily VerbruggeDepartment of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA.
Daniel D WiegmannDepartment of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA.
John J LiPumaDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Hans WildschutteDepartment of Biological Sciences, Bowling Green State University, Bowling Green, Ohio, USA hansw@bgsu.edu.
Bowling Green State University · USUniversity of Michigan–Ann Arbor · US

Funding

Genetic basis of metabolite production against clinically-derived pathogensR15GM124585 · NIGMS · BOWLING GREEN STATE UNIVERSITY · PI WILDSCHUTTE, HANS · 2018 to 2023
$960k
NIGMS NIH HHS R15 GM124585
6 · The paper itself

Abstract

Since the discovery of penicillin, microbes have been a source of antibiotics that inhibit the growth of pathogens. However, with the evolution of multidrug-resistant (MDR) strains, it remains unclear if there is an abundant or limited supply of natural products to be discovered that are effective against MDR isolates. To identify strains that are antagonistic to pathogens, we examined a set of 471 globally derived environmental

Indexed as

Drug Resistance, Multiple, BacterialAnti-Bacterial AgentsAntibiosisBacteriaMicrobial Sensitivity TestsPseudomonasAnti-Bacterial Agentsantagonisticantibioticbiosynthetic gene clustermultidrug resistancePseudomonastransposon mutagenesis

Identifiers

PMID31540982
PMCPMC6856318
OpenAlexW2973499900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.