SynthesisClinical journal of the American Society of Nephrology : CJASN2019
Risk Factors for 1-Year Graft Loss After Kidney Transplantation: Systematic Review and Meta-Analysis.
Synthesis in Clinical journal of the American Society of Nephrology : CJASN, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04705402 (A Prospective, Randomized, Double Blinded, Placebo Control Trial to Evaluate Efficacy of Intravenous Mannitol Use During Cadaveric Kidney Transplantation Prior to Kidney Reperfusion), which is not on this map. Cited by 61 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective, Randomized, Double Blinded, Placebo Control Trial to Evaluate Efficacy of Intravenous Mannitol Use During Cadaveric Kidney Transplantation Prior to Kidney Reperfusion
Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Sex as a prognostic factor for mortality in adults with acute symptomatic pulmonary embolism.The Cochrane database of systematic reviews · 2025Pooled it
- Handgrip strength and all-cause mortality in patients with chronic kidney disease: an updated systematic review and meta-analysis of cohort studies.International urology and nephrology · 2023Pooled it
- Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipients.The Cochrane database of systematic reviews · 2022Pooled it
- Renal Function Improvement Following ANG-3777 Treatment in Patients at High Risk for Delayed Graft Function After Kidney Transplantation.Transplantation · 2021Trial
- First-year all-cause kidney allograft loss: descriptive clinical trajectories of 92 events from a 17-year German transplant center cohort.BMC nephrology · 2026Article
- Predicting first-year kidney graft loss at the time of donor offer using machine learning and competing-risk analysis in a Latin American cohort.Clinical kidney journal · 2026Article
- Impact of donor-recipient ethnic matching on survival after lung transplantation in Italy.Updates in surgery · 2026Article
- Tubular MAG3 Extraction Rate is a Predictor of Short-Term and Long-Term Outcome After Kidney Transplantation: A Prospective Observational Study.Clinical nuclear medicine · 2026Observational
- Quantifying Center-level Aggressiveness in Transplanting Suboptimal, Deceased Donor Kidneys in the United States.Transplantation direct · 2026Article
- Anti-obesity Pharmacotherapy for Transplant Recipients.Current atherosclerosis reports · 2026Review
- Age-specific impact of different immunosuppressive regimens on kidney transplant outcomes: clinical evidence from the scientific registry of transplant recipients.Frontiers in nephrology · 2026Article
- The obese transplant organ recipient: experimental and clinical evidence for tailored immunosuppression.Transplant international : official journal of the European Society for Organ Transplantation · 2026Review
- Comparative Analysis of Graft Survival in Older and Younger Kidney Transplant Recipients: A Single-Center Cohort Study.Journal of clinical medicine · 2025Article
- Impact of delayed graft function on overall and graft survival in recipients of deceased donor kidney transplants.BMC nephrology · 2025Article
- Trends and outcomes in kidney retransplantation: a 2-decade longitudinal analysis.International urology and nephrology · 2025Article
- Longitudinal multi-b-value diffusion-weighted imaging in renal transplant recipients: diagnostic efficacy and prognostic value for allograft dysfunction.Quantitative imaging in medicine and surgery · 2025Article
- Effects of the pretransplant obesity on kidney transplant outcomes in Korea: a nationwide cohort study.BMC nephrology · 2025Article
- Orai1 Expression and Vascular Function in Kidney Donors Determine Graft Outcomes at Short/Mid-Term.Cells · 2025Article
- Association Between Perioperative Hypotension and Graft Function in Kidney Transplantation.Kidney international reports · 2025Article
- Surgical and Infectious Complications Following Kidney Transplantation: A Contemporary Review.Journal of clinical medicine · 2025Review
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesWith expansion of the pool of kidney grafts, through the use of higher-risk donors, and increased attention to donor management strategies, the 1-year graft survival rate is subject to change. It is, therefore, useful to elucidate 1-year graft survival rates by dissecting the characteristics of the low-risk and high-risk kidney transplant cases. The objective of our study was to evaluate factors purported to influence the risk of 1-year graft loss in kidney transplant recipients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We searched bibliographic databases from 2000 to 2017 and included observational studies that measured the association between donor, recipient, the transplant operation, or early postoperative complications, and 1-year death-censored graft loss.
resultsWe identified 35 eligible primary studies, with 20 risk factors amenable to meta-analysis. Six factors were associated with graft loss, with moderate to high degree of certainty: donor age (hazard ratio [HR], 1.11 per 10-year increase; 95% confidence interval [95% CI], 1.04 to 1.18), extended criteria donors (HR, 1.35; 95% CI, 1.28 to 1.42), deceased donors (HR, 1.54; 95% CI, 1.32 to 1.82), number of HLA mismatches (HR, 1.08 per one mismatch increase; 95% CI, 1.07 to 1.09), recipient age (HR, 1.17 per 10-year increase; 95% CI, 1.09 to 1.25), and delayed graft function (HR, 1.89; 95% CI, 1.46 to 2.47) as risk factors for 1-year graft loss. Pooled analyses also excluded, with a high degree of certainty, any associations of cold ischemia time, recipient race, pretransplant body mass index, diabetes, and hypertension with 1-year graft loss.
conclusionsRecipient age, donor age, standard versus extended criteria donor, living versus deceased donor, HLA mismatch, and delayed graft function all predicted 1-year graft survival. The effect of each risk factor is small.
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