Evidence map›Paper›PMID 31540911›Full record

ArticleHospital pediatrics2019

Factors Associated With Asthma Diagnosis Within Five Years of a Bronchiolitis Hospitalization: A Retrospective Cohort Study in a High Asthma Prevalence Population.

Amanda J Clark, Nancy Dong, Talia Roth, Lindsey C Douglas

Abstract read
In one paragraph

Article in Hospital pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Amanda J ClarkDivision of Pediatric Nephrology, Boston Children's Hospital, Boston, Massachusetts.
Nancy DongAlbert Einstein College of Medicine, Bronx, New York.
Talia RothDepartment of Pediatrics, Jacobi Medical Center, Bronx, New York; and.
Lindsey C DouglasPediatric Hospital Medicine, Mount Sinai Kravis Children's Hospital, New York, New York lindsey.douglas@mssm.edu.
Albert Einstein College of Medicine · USBoston Children's Hospital · USJacobi Medical Center · US

Funding

RESEARCH TRAINING IN PEDIATRIC NEPHROLOGYT32DK007726 · NIDDK · CHILDREN'S HOSPITAL BOSTON · PI BRISCOE, DAVID M. · 1994 to 2023
$5.9M
NIDDK NIH HHS T32 DK007726
6 · The paper itself

Abstract

objectivesBronchiolitis, the leading cause of infant hospitalizations in the United States, is associated with increased risk of childhood asthma. We hypothesized that factors during a bronchiolitis hospitalization were associated with subsequent asthma.

methodsThis is a retrospective cohort study at an urban, tertiary-care children's hospital of infants <12 months old, hospitalized for bronchiolitis. The primary outcome measure was an asthma diagnosis, defined as a billing code for an asthma visit or a prescription for controller medication, within 5 years of discharge from the bronchiolitis hospitalization.

resultsThere were 534 infants hospitalized for bronchiolitis, of which 294 (55.1%) were diagnosed with asthma, and 102 (19.1%) were hospitalized for asthma within 5 years of discharge. There was significant interaction between age and family history. In both models, female sex was protective (odds ratio [OR] 0.46). Age and race were only associated with asthma in infants without a family history of asthma: age (OR 1.19; 95% confidence interval 1.08-1.32) and race (OR 4.06; 95% confidence interval 1.56-10.58). Hospitalization length, ICU stay, albuterol treatments received, supplemental oxygen, respiratory support, highest respiratory rate, and respiratory syncytial virus infection were not associated with asthma diagnosis.

conclusionsMore than 55% of infants hospitalized for bronchiolitis developed asthma within 5 years of discharge. Demographic and family history variables were independently associated with asthma. However, hospital-based variables during the bronchiolitis hospitalization were not independently associated with asthma. These results can direct further research and differentiate anticipatory guidance for infants with bronchiolitis at risk for asthma.

Indexed as

HospitalizationAge FactorsAsthmaBronchiolitisChild, PreschoolEthnicityFemaleFollow-Up StudiesHumansInfantMalePrevalenceRespiratory Syncytial Virus InfectionsRetrospective StudiesRisk Factors

Identifiers

PMID31540911
PMCPMC7057997
OpenAlexW2978947907

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.