Evidence map›Paper›PMID 31540616›Full record

SynthesisJournal of substance abuse treatment2019

Change in employment status and cocaine use treatment outcomes: A secondary analysis across six clinical trials.

André Q C Miguel, Brian D Kiluk, Corey R Roos, Theresa A Babuscio, Charla Nich, Jair J Mari, Kathleen M Carroll

Open access · greenAbstract readMeta-Analysis
In one paragraph

Synthesis in Journal of substance abuse treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Association Between Unemployment and Mental Disorders: A Narrative Update of the Literature.International journal of environmental research and public health · 2024
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

André Q C MiguelElson S. Floyd College of Medicine, Washington State University, Spokane, WA, United States; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States; Department of Psychiatry, Federal University of Sao Paulo, Sao Paulo, Brazil. Electronic address: andre.miguel@wsu.edu.
Brian D KilukDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, United States.
Corey R RoosDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, United States.
Theresa A BabuscioDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, United States.
Charla NichDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, United States.
Jair J MariDepartment of Psychiatry, Federal University of Sao Paulo, Sao Paulo, Brazil.
Kathleen M CarrollDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, United States.
Yale University · USUniversidade Federal de São Paulo · BR

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
TSF to enhance treatment of cocaine dependenceP50DA009241 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 1994 to 2018
$40.5M
The National Drug Abuse Treatment Clinical Trials Network (U10)U10DA015831 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI CARROLL, KATHLEEN M., WEISS, ROGER D. · 2002 to 2015
$28.8M
Computer-Based Training in Cognitve Behavioral TherapyR01DA015969 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 2002 to 2015
$2.8M
Computer Based Training in CBT for Spanish-Speaking Substance Users: Competitive RevisionR01DA030369 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M., PARIS, MANUEL · 2012 to 2017
$2.6M
Identification of a Meaningful Cocaine Use Outcome MeasureR33DA041661 · NIDA · YALE UNIVERSITY · PI KILUK, BRIAN D. · 2018 to 2020
$1.1M
Identification of a Meaningful Cocaine Use Outcome MeasureR21DA041661 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M., KILUK, BRIAN D. · 2016 to 2017
$456k
NCATS NIH HHS UL1 TR001863NIDA NIH HHS P50 DA009241NIDA NIH HHS R01 DA015969NIDA NIH HHS R01 DA030369NIDA NIH HHS R21 DA041661NIDA NIH HHS R33 DA041661NIDA NIH HHS U10 DA015831
6 · The paper itself

Abstract

backgroundUnemployment is a chronic problem among treatment seeking substance users and is associated with poor treatment response. Most studies that have examined the relationship between employment and treatment outcomes for substance use disorders have done so by considering employment at only one specific point in time (e.g., upon entering treatment). There is a lack of research on how change in employment status over time is associated with substance use treatment outcomes. The aim of this study was to evaluate both static employment status and change in employment status over time as predictors of cocaine use treatment outcomes.

methodsWe utilized data pooled from six randomized clinical trials evaluating treatment for cocaine use disorders (n = 553). Multiple general linear mixed models were conducted to determine the association of baseline, end-of-treatment, and change in employment status (from baseline to end-of-treatment) with treatment outcomes.

resultsTreatment outcomes did not differ by baseline employment status but were significantly better for those employed versus unemployed at the end-of-treatment. In regard to change in employment status over time, those who were unemployed at baseline and acquired employment by end-of-treatment had significantly better treatment outcomes during active treatment and follow-up, as compared to those who were unemployed at baseline and remained unemployed by end-of-treatment.

conclusionOur findings suggest that end-of-treatment employment status may be an important marker of good outcome among those unemployed at treatment entry and support the incorporation of interventions designed to promote employment by substance use disorders treatment programs.

Indexed as

AdultCocaine-Related DisordersEmploymentFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicTreatment OutcomeUnemploymentCocaine use disordersEmploymentPharmacological interventionPsychosocial interventionRandomized clinical trialTreatment outcomes

Identifiers

PMID31540616
PMCPMC6785033
OpenAlexW2971748763

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.