ArticleMolecules (Basel, Switzerland)2019
Formation and Stabilization of Gold Nanoparticles in Bovine Serum Albumin Solution.
Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 59 citations in OpenAlex.
- Surface-enhanced stimulated Raman scattering and fluorescence probing of plasmonic nanoparticles in cellular environments: insights into their spatial distribution and aggregation.Nanoscale advances · 2026Article
- Panobinostat-Loaded Albumin Nanoparticles for the Treatment of Pancreatic Cancer.Journal of drug delivery science and technology · 2025Article
- Effect of Gold Nanoparticles and Coexisting Acetonitrile Solvent on the Structure of Bovine Serum Albumin.ACS omega · 2025Article
- Antibiotic-Mediated Plasmonic-Mie Resonance for Biosensing Applications on a Novel Silicon Nanopillar Metasurface.Advanced materials interfaces · 2025Article
- Better together: biomimetic nanomedicines for high performance tumor therapy.Beilstein journal of nanotechnology · 2025Review
- Article
- The phototoxic effect of a gold-antibody-based nanocarrier of phthalocyanine on melanoma monolayers and tumour spheroids.RSC advances · 2024Article
- Tau- and α-synuclein-targeted gold nanoparticles: applications, opportunities, and future outlooks in the diagnosis and therapy of neurodegenerative diseases.Journal of nanobiotechnology · 2024Review
- Design consideration of phthalocyanines as sensitizers for enhanced sono-photodynamic combinatorial therapy of cancer.Acta pharmaceutica Sinica. B · 2024Review
- Using Sparfloxacin-Capped Gold Nanoparticles to Modify a Screen-Printed Carbon Electrode Sensor for Ethanol Determination.Sensors (Basel, Switzerland) · 2023Article
- Green synthesis, characterization, and biological evaluation of gold and silver nanoparticles using Mentha spicata essential oil.Scientific reports · 2023Article
- Laser Ablated Albumin Functionalized Spherical Gold Nanoparticles Indicated for Stem Cell Tracking.Materials (Basel, Switzerland) · 2023Article
- Emerging Albumin-Binding Anticancer Drugs for Tumor-Targeted Drug Delivery: Current Understandings and Clinical Translation.Pharmaceutics · 2022Review
- Biomimetic Radical Chemistry and Applications.Molecules (Basel, Switzerland) · 2022Article
- Complete ablation of tumors using synchronous chemoradiation with bimetallic theranostic nanoparticles.Bioactive materials · 2022Article
- Bio-Specific Au/FeBiosensors · 2021Article
- Bovine Serum Albumin-Immobilized Black Phosphorus-Based γ-FeBiomedicines · 2021Article
- Effect of Serum on Electrochemical Detection of Bioassays Having Ag Nanoparticle Labels.ACS sensors · 2021Article
- Synthesis and Stabilization of Gold Nanoparticles Using Water-Soluble Synthetic and Natural Polymers.Polymers · 2020Article
- Isolation methods for particle protein corona complexes from protein-rich matrices.Nanoscale advances · 2020Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The formation and growth of gold nanoparticles (AuNPs) were investigated in pH 7 buffer solution of bovine serum albumin (BSA) at room temperature. The processes were monitored by UV-Vis, circular dichroism, Raman and electron paramagnetic resonance (EPR) spectroscopies. TEM microscopy and dynamic light scattering (DLS) measurements were used to evidence changes in particle size during nanoparticle formation and growth. The formation of AuNPs at pH 7 in the absence of BSA was not observed, which proves that the albumin is involved in the first step of Au(III) reduction. Changes in the EPR spectral features of two spin probes, CAT16 and DIS3, with affinity for BSA and AuNPs, respectively, allowed us to monitor the particle growth and to demonstrate the protective role of BSA for AuNPs. The size of AuNPs formed in BSA solution increases slowly with time, resulting in nanoparticles of different morphologies, as revealed by TEM. Raman spectra of BSA indicate the interaction of albumin with AuNPs through sulfur-containing amino acid residues. This study shows that albumins act as both reducing agents and protective corona of AuNPs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.