Evidence map›Paper›PMID 31540496›Full record

ArticleMolecules (Basel, Switzerland)2019

(10

Seon Min Lee, Na-Hyun Kim, Sangbum Lee, Yun Na Kim, Jeong-Doo Heo, Jung-Rae Rho, Eun Ju Jeong

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Bioactive potency of extracts fromBiomedical reports · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Microorganisms · 2022
    Article
  7. Article
  8. Article
  9. NMR of Natural Products as Potential Drugs.Molecules (Basel, Switzerland) · 2021
    Review
  10. Article
  11. Frontiers in immunology · 2021
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Seon Min LeeGyeongnam Department of Environment & Toxicology, Korea Institute of Toxicology, 17 Jegok-gil, Munsan-eup 52834, Korea. smlee84@kitox.re.kr.
Na-Hyun KimGyeongnam Department of Environment & Toxicology, Korea Institute of Toxicology, 17 Jegok-gil, Munsan-eup 52834, Korea. nhkim@kitox.re.kr.
Sangbum LeeDepartment of Oceanography, Kunsan National University, Kunsan 54150, Korea. sblee08@kunsan.ac.kr.
Yun Na KimDepartment of Agronomy and Medicinal Plant Resources, Gyeongnam National University of Science and Technology, Jinju 52725, Korea. skdbssk@hanmail.net.ORCID 0000-0002-8408-3012
Jeong-Doo HeoGyeongnam Department of Environment & Toxicology, Korea Institute of Toxicology, 17 Jegok-gil, Munsan-eup 52834, Korea. jdher@kitox.re.kr.
Jung-Rae RhoDepartment of Oceanography, Kunsan National University, Kunsan 54150, Korea. jrrho@kunsan.ac.kr.
Eun Ju JeongDepartment of Agronomy and Medicinal Plant Resources, Gyeongnam National University of Science and Technology, Jinju 52725, Korea. ejjeong@gntech.ac.kr.
Kunsan National University · KRGyeongnam National University of Science and Technology · KRKorea Institute of Toxicology · KR

Funding

Marine Biotechnology Program funded by the Ministry of Oceans and Fisheries, Korea. 20170488
6 · The paper itself

Abstract

Crohn's disease (CD) and ulcerative colitis (UC), collectively referred to as inflammatory bowel disease (IBD), are autoimmune diseases characterized by chronic inflammation within the gastrointestinal tract. Debromohymenialdisine is an active pyrrole alkaloid that is well known to serve as a stable and effective inhibitor of Chk2. In the present study, we attempted to investigate the anti-inflammatory properties of (10

Indexed as

Colitis, UlcerativeCrohn DiseaseAnimalsAquatic OrganismsAzepinesCaco-2 CellsCoculture TechniquesDinoprostoneHumansInflammationInterleukin-1betaInterleukin-6IntestinesPoriferaPyrrolesTHP-1 CellsAzepinesdebromohymenialdisineDinoprostoneIL1B protein, humanIL6 protein, humanInterleukin-1betaInterleukin-6Pyrroles(10Z)-debromohymenialdisineCaco-2co-cultureinflammationinflammatory bowel diseaseStylissa sp.THP-1

Identifiers

PMID31540496
PMCPMC6766964
OpenAlexW2974587458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.