Evidence map›Paper›PMID 31540454›Full record

ArticleBiomolecules2019

Effects of Fludioxonil on the Cell Growth and Apoptosis in T and B Lymphocytes.

Gun-Hwi Lee, Kyung-A Hwang, Kyung-Chul Choi

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gun-Hwi LeeLaboratory of Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. rha131@naver.com.
Kyung-A HwangLaboratory of Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. hka9400@naver.com.
Kyung-Chul ChoiLaboratory of Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk 28644, Korea. kchoi@cbu.ac.kr.ORCID 0000-0002-1925-1198
Chungbuk National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fludioxonil is fungicide used in agriculture, which is present in fruits and vegetables. In this study, the effects of fludioxonil on human immune cell viability, apoptosis, cell cycle arrest, and mitochondrial membrane potential were examined in human immune cells, such as Jurkat T cells and Ramos B cells. To examine the cell viability, Jurkat T cells and Ramos B cells were treated with fludioxonil (10

Indexed as

bcl-2-Associated X ProteinB-LymphocytesCaspase 3Cell CycleCell LineCell ProliferationCell SurvivalCyclin D1Cyclin EDioxolesFungicides, IndustrialGene Expression RegulationHumansJurkat CellsMembrane Potential, MitochondrialOncogene ProteinsBAX protein, humanbcl-2-Associated X ProteinBCL2 protein, humanCASP3 protein, humanCaspase 3CCND1 protein, humanCCNE1 protein, humanCyclin D1Cyclin EDioxolesfludioxonilFungicides, IndustrialOncogene ProteinsProto-Oncogene Proteins c-bcl-2PyrrolesTP53 protein, humanTumor Suppressor Protein p53apoptosiscell cycle arrestfludioxonillymphocyte

Identifiers

PMID31540454
PMCPMC6770511
OpenAlexW2973295346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.