Evidence map›Paper›PMID 31540413›Full record

ReviewCells2019

New Insights into the Liver-Visceral Adipose Axis During Hepatic Resection and Liver Transplantation.

María Eugenia Cornide-Petronio, Mónica B Jiménez-Castro, Jordi Gracia-Sancho, Carmen Peralta

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

María Eugenia Cornide-PetronioInstitut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), 08036 Barcelona, Spain. cornide@clinic.cat.ORCID 0000-0002-1623-8131
Mónica B Jiménez-CastroInstitut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), 08036 Barcelona, Spain. monicabjimenez@hotmail.com.ORCID 0000-0002-5890-1042
Jordi Gracia-SanchoLiver Vascular Biology Research Group, Barcelona Hepatic Hemodynamic Laboratory IDIBAPS, 08036 Barcelona, Spain. jgracia@clinic.cat.ORCID 0000-0001-7736-4089
Carmen PeraltaInstitut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), 08036 Barcelona, Spain. cperalta@clinic.cat.ORCID 0000-0002-5767-0676
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ES

Funding

DNA Repair and Checkpoint Interactions in MammalsR01CA095114 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI MCGOWAN, CLARE H · 2003 to 2008
$1.7M
6 · The paper itself

Abstract

In the last decade, adipose tissue has emerged as an endocrine organ with a key role in energy homeostasis. In addition, there is close crosstalk between the adipose tissue and the liver, since pro- and anti-inflammatory substances produced at the visceral adipose tissue level directly target the liver through the portal vein. During surgical procedures, including hepatic resection and liver transplantation, ischemia-reperfusion injury induces damage and regenerative failure. It has been suggested that adipose tissue is associated with both pathological or, on the contrary, with protective effects on damage and regenerative response after liver surgery. The present review aims to summarize the current knowledge on the crosstalk between the adipose tissue and the liver during liver surgery. Therapeutic strategies as well as the clinical and scientific controversies in this field are discussed. The different experimental models, such as lipectomy, to evaluate the role of adipose tissue in both steatotic and nonsteatotic livers undergoing surgery, are described. Such information may be useful for the establishment of protective strategies aimed at regulating the liver-visceral adipose tissue axis and improving the postoperative outcomes in clinical liver surgery.

Indexed as

Liver TransplantationAnimalsHumansIntra-Abdominal FatLiveradipose tissueinflammationlipectomyliverliver resectionliver transplantationsteatosis

Identifiers

PMID31540413
PMCPMC6769706
OpenAlexW2973993463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.