ArticleCancers2019
Prognostic Factors for Event-Free Survival in Pediatric Patients with Hepatoblastoma Based on the 2017 PRETEXT and CHIC-HS Systems.
Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Improving image quality and diagnostic confidence for PRETEXT staging in pediatric hepatoblastoma using thin-slice and low-energy virtual monochromatic images in dual-energy CT with deep learning image reconstruction algorithm.BMC medical imaging · 2026Article
- Development of a machine learning-based prognostic prediction model and a web-based tool for pediatric hepatoblastoma: a Surveillance, Epidemiology, and End Results (SEER) database study.Pediatric surgery international · 2026Article
- Magnetic resonance imaging-based deep-learning radiomics score for survival prediction and risk stratification in pediatric hepatoblastoma receiving surgical resection.World journal of radiology · 2026Article
- Prognostic Value of POST-Treatment Extent of Tumor (POSTTEXT) System in Patients with Hepatoblastoma.Cancer research and treatment · 2025Article
- Metabolic and Epigenetic Mechanisms in Hepatoblastoma: Insights into Tumor Biology and Therapeutic Targets.Genes · 2024Review
- Usefulness of central radiologic review in clinical trials of children with hepatoblastoma.Pediatric radiology · 2023Article
- Elevated serum uric acid is associated with the risk of advanced staging and vascular involvement in patients with hepatoblastoma: a 14-year retrospective study.Frontiers in oncology · 2023Article
- Surgical resection of pediatric PRETEXT III and IV hepatoblastoma: A retrospective study investigating the need for preoperative chemotherapy.Frontiers in pediatrics · 2022Article
- Outcome of staging chest CT and identification of factors associated with lung metastasis in children with hepatoblastoma.European radiology · 2021Article
- [Clinical features and prognostic analysis of hepatoblastoma in children under six years old].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2021Article
- [Imaging of hepatic tumors in children and adolescents].Der Radiologe · 2021Review
- Recent improvement in survival outcomes and reappraisal of prognostic factors in hepatoblastoma.Cancer medicine · 2021Article
- Two-stage laparoscopic resection of giant hepatoblastoma in infants combined with liver partial partition and artery ligation.World journal of surgical oncology · 2021Article
- Preoperative Assessment for Event-Free Survival With Hepatoblastoma in Pediatric Patients by Developing a CT-Based Radiomics Model.Frontiers in oncology · 2021Article
- Factors influencing recurrence after complete remission in children with hepatoblastoma: A 14-year retrospective study in China.PloS one · 2021Article
- CHIC Risk Stratification System for Predicting the Survival of Children With Hepatoblastoma: Data From Children With Hepatoblastoma in China.Frontiers in oncology · 2020Article
- Congenital Hepatoblastoma in a Female Neonate: A Case Report.Case reports in oncologyArticle
Corrections and comments
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8 authors.
Funding
Abstract
This study aimed to evaluate the prognostic value of variables used in the 2017 PRE-Treatment EXTent of tumor (PRETEXT) system and the Children's Hepatic tumors International Collaboration-Hepatoblastoma Stratification (CHIC-HS) system in pediatric patients with hepatoblastoma. A retrospective analysis of data from the pediatric hepatoblastoma registry of a tertiary referral center was conducted to evaluate the clinical and imaging variables (annotation factors) of the PRETEXT staging system. The primary outcome was event-free survival (EFS). Data from 84 patients (mean age: 2.9 ± 3.5 years) identified between 1998 and 2017 were included. Univariable Cox proportional hazards analysis revealed that PRETEXT annotation factors P (portal vein involvement), F (multifocality of tumor), and M (distant metastasis) showed a significant negative association with EFS. Multivariable Cox proportional hazard analysis showed that factor F was the strongest predictor (HR (hazard ratio), 2.908; 95% CI (confidence interval), 1.061-7.972;
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