Evidence map›Paper›PMID 31540386›Full record

ArticleInternational journal of molecular sciences2019

Fluorescent Radiosensitizing Gold Nanoparticles.

Gloria Jiménez Sánchez, Pauline Maury, Lenka Stefancikova, Océane Campion, Gautier Laurent, Alicia Chateau, Farhan Bouraleh Hoch, Frédéric Boschetti, Franck Denat, Sophie Pinel and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. The Physical Chemistry and Chemical Physics (PCCP) Section of theInternational journal of molecular sciences · 2021
    Article
  9. Review
  10. Increased carcinoembryonic antigen expression on the surface of lung cancer cells using gold nanoparticles during radiotherapy.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2020
    Article
  11. Nanoparticle-Based Radiosensitization.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Gloria Jiménez SánchezInstitut Univers, Temps-fréquence, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UTINAM), UMR 6213 CNRS-UBFC, Université Bourgogne Franche-Comté, 25030 Besançon CEDEX, France. gloria.jimenez.sanch@gmail.com.
Pauline MauryInstitut des Sciences Moléculaires d'Orsay, UMR 8214 CNRS-UPS, Université Paris-Sud, 91405 Orsay CEDEX, France. pauline.maury@u-psud.fr.
Lenka StefancikovaInstitut des Sciences Moléculaires d'Orsay, UMR 8214 CNRS-UPS, Université Paris-Sud, 91405 Orsay CEDEX, France. llanayau@gmail.com.
Océane CampionMatrice Extracellulaire et Dynamique Cellulaire, MEDyC, UMR 7369 CNRS-URCA, Université de Reims Champagne-Ardenne, 51687 Reims CEDEX 2, France. Oceane.Campion@mrsolutions.com.
Gautier LaurentInstitut Univers, Temps-fréquence, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UTINAM), UMR 6213 CNRS-UBFC, Université Bourgogne Franche-Comté, 25030 Besançon CEDEX, France. gautier.laurent0@gmail.com.ORCID 0000-0002-8544-1379
Alicia ChateauCentre de Recherche en Automatique de Nancy, Département Biologie, Signaux et Systèmes en Cancérologie et Neurosciences, UMR 7039 CNRS-UL, Université de Lorraine, 54505 Vandœuvre-lès-Nancy, France. alicia.chateau@univ-lorraine.fr.
Farhan Bouraleh HochInstitut Univers, Temps-fréquence, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UTINAM), UMR 6213 CNRS-UBFC, Université Bourgogne Franche-Comté, 25030 Besançon CEDEX, France. youyin_08@hotmail.com.
Frédéric BoschettiCheMatech, 21000 Dijon, France. fboschetti@chematech-mdt.com.
Franck DenatInstitut de Chimie Moléculaire de l'Université de Bourgogne (ICMUB), UMR 6302 CNRS-UBFC, Université Bourgogne Franche-Comté, 21078 Dijon CEDEX, France. franck.denat@u-bourgogne.fr.ORCID 0000-0002-9652-4006
Sophie PinelCentre de Recherche en Automatique de Nancy, Département Biologie, Signaux et Systèmes en Cancérologie et Neurosciences, UMR 7039 CNRS-UL, Université de Lorraine, 54505 Vandœuvre-lès-Nancy, France. sophie.pinel@univ-lorraine.fr.
Jérôme DevyMatrice Extracellulaire et Dynamique Cellulaire, MEDyC, UMR 7369 CNRS-URCA, Université de Reims Champagne-Ardenne, 51687 Reims CEDEX 2, France. jerome.devy@univ-reims.fr.ORCID 0000-0003-2703-8167
Erika PorcelInstitut des Sciences Moléculaires d'Orsay, UMR 8214 CNRS-UPS, Université Paris-Sud, 91405 Orsay CEDEX, France. erika.porcel@u-psud.fr.ORCID 0000-0001-8048-4276
Sandrine LacombeInstitut des Sciences Moléculaires d'Orsay, UMR 8214 CNRS-UPS, Université Paris-Sud, 91405 Orsay CEDEX, France. sandrine.lacombe@u-psud.fr.ORCID 0000-0003-3334-9201
Rana BazziInstitut Univers, Temps-fréquence, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UTINAM), UMR 6213 CNRS-UBFC, Université Bourgogne Franche-Comté, 25030 Besançon CEDEX, France. rana.bazzi@univ-fcomte.fr.
Stéphane RouxInstitut Univers, Temps-fréquence, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UTINAM), UMR 6213 CNRS-UBFC, Université Bourgogne Franche-Comté, 25030 Besançon CEDEX, France. stephane.roux@univ-fcomte.fr.ORCID 0000-0002-5198-1916
Centre National de la Recherche Scientifique · FRUniversité Paris-Sud · FR

Funding

Agence Nationale de la Recherche ANR 2012 RPIB 0010CANCEROPOLE EST 2016Y-8938Centre National de la Recherche Scientifique Défi NanoConseil Régional de Franche-Comté 2013-0107Seventh Framework Programme FP7-PEOPLE-2013-IEF-624370Seventh Framework Programme FP7-PEOPLE-2013-ITN-608163
6 · The paper itself

Abstract

Ultrasmall polyaminocarboxylate-coated gold nanoparticles (NPs), Au@DTDTPA and Au@TADOTAGA, that have been recently developed exhibit a promising potential for image-guided radiotherapy. In order to render the radiosensitizing effect of these gold nanoparticles even more efficient, the study of their localization in cells is required to better understand the relation between the radiosensitizing properties of the agents and their localization in cells and in tumors. To achieve this goal, post-functionalization of Au@DTDTPA nanoparticles by near-infrared (NIF) organic dyes (aminated derivative of cyanine 5, Cy5-NH

Indexed as

AnimalsCarbocyaninesCell Line, TumorFemaleFluorescent DyesGoldHumansMetal NanoparticlesMiceMice, Inbred BALB CMice, NudeMicroscopy, FluorescenceNeoplasmsOptical ImagingPolyaminesRadiation-Sensitizing AgentsCarbocyaninescyanine dye 5Fluorescent DyesGoldPolyaminesRadiation-Sensitizing Agentsfluorescence imaginggold nanoparticlesradiosensitization

Identifiers

PMID31540386
PMCPMC6770707
OpenAlexW2974768847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.