Evidence map›Paper›PMID 31540365›Full record

ArticleMaterials (Basel, Switzerland)2019

New Poly(Propylene Imine) Dendrimer Modified with Acridine and Its Cu(II) Complex: Synthesis, Characterization and Antimicrobial Activity.

Paula Bosch, Desislava Staneva, Evgenia Vasileva-Tonkova, Petar Grozdanov, Ivanka Nikolova, Rositsa Kukeva, Radostina Stoyanova, Ivo Grabchev

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Light-driven self-sterilizing cotton fabric and drug delivery: improvement of the antimicrobial activity of 4-sulfo-1,8-naphthalimide via its dendrimer and metallic dendrimer formation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Paula BoschInstitute of Science and Technology of Polymers, Institute of Science and Technology of Polymers-Spanish National Research Council (ICTP-CSIC), Juan de la Cierva 3, 28006 Madrid, Spain. pbosch@ictp.csic.es.
Desislava StanevaDepartment of Chemical Technology, University of Chemical Technology and Metallurgy, 1756 Sofia, Bulgaria. grabcheva@mail.bg.
Evgenia Vasileva-TonkovaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria. Evaston@yahoo.com.
Petar GrozdanovThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria. grozdanov_bg@yahoo.com.ORCID 0000-0003-2788-382X
Ivanka NikolovaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria. vanianik@mail.bg.
Rositsa KukevaInstitute of General and Inorganic Chemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria. rositsakukeva@yahoo.com.
Radostina StoyanovaInstitute of General and Inorganic Chemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria. radstoy@svr.igic.bas.bg.
Ivo GrabchevFaculty of Medicine, Sofia University "St. Kliment Ohridski", 1407 Sofia, Bulgaria. i.grabchev@chem.uni-sofia.bg.ORCID 0000-0001-7204-8183
Bulgarian Academy of Sciences · BGConsejo Superior de Investigaciones Científicas · ESSofia University "St. Kliment Ohridski" · BGUniversity of Chemical Technology and Metallurgy · BG

Funding

Fund "Scientific Research", Ministry of Education and Science of Bulgaria КОСТ 01/24-2017Ministry of Economy and Competitively of Spain RTI2018-096328-B-I00
6 · The paper itself

Abstract

A second-generation poly(propylene imine) dendrimer modified with acridine and its Cu(II) complex have been synthesized for the first time. It has been found that two copper ions form complexes with the nitrogen atoms of the dendrimeric core by coordinate bonds. The new compounds have been characterized by nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR), fourier-transform infrared spectroscopy (FTIR) and fluorescence spectroscopy. The spectral characteristics of the modified dendrimer have been measured in different organic solvents, and a negative fluorescence solvatochromism has been observed. The antimicrobial activity of the dendrimers has been tested against model pathogenic microorganisms in agar and by broth dilution method. The cotton fabric treated with both dendrimers has been evaluated towards pathogenic microorganisms. The obtained modified cotton fabrics have been shown to hamper bacterial growth and to prevent biofilm formation. Dendrimer cytotoxicity has been investigated in vitro in the model HEp-2 cell line.

Indexed as

acridineantibacterial cottonantimicrobial activitydendrimermetallodendrimer

Identifiers

PMID31540365
PMCPMC6766332
OpenAlexW2973767429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.