Evidence map›Paper›PMID 31540361›Full record

ReviewInternational journal of molecular sciences2019

Reparative and Regenerative Effects of Mesenchymal Stromal Cells-Promising Potential for Kidney Transplantation?

Merel Pool, Henri Leuvenink, Cyril Moers

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Extracorporeal Photopheresis Improves Graft Survival in a Full-Mismatch Rat Model of Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Merel PoolDepartment of Surgery-Organ Donation and Transplantation, University Medical Center Groningen, 9713GZ Groningen, The Netherlands. m.b.f.pool@umcg.nl.ORCID 0000-0003-4914-8981
Henri LeuveninkDepartment of Surgery-Organ Donation and Transplantation, University Medical Center Groningen, 9713GZ Groningen, The Netherlands. h.g.d.leuvenink@umcg.nl.
Cyril MoersDepartment of Surgery-Organ Donation and Transplantation, University Medical Center Groningen, 9713GZ Groningen, The Netherlands. c.moers@umcg.nl.ORCID 0000-0001-8014-8387
University Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stromal cells (MSCs) possess reparative, regenerative and immunomodulatory properties. The current literature suggests that MSCs could improve kidney transplant outcome via immunomodulation. In many clinical domains, research has also focussed on the regenerative and reparative effects of therapies with MSCs. However, in the field of transplantation, data on this subject remain scarce. This review provides an overview of what is known about the regenerative and reparative effects of MSCs in various fields ranging from wound care to fracture healing and also examines the potential of these promising MSC properties to improve the outcome of kidney transplantations.

Indexed as

Wound HealingAcute Kidney InjuryAnimalsHumansImmunomodulationKidney TransplantationMesenchymal Stem CellsMesenchymal Stem Cell TransplantationRegenerative MedicineTreatment Outcomekidney transplantationmesenchymal stromal cellsregeneration

Identifiers

PMID31540361
PMCPMC6770554
OpenAlexW2973773932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.