Evidence map›Paper›PMID 31540349›Full record

ReviewInternational journal of molecular sciences2019

Co-Operation between Aneuploidy and Metabolic Changes in Driving Tumorigenesis.

David L Newman, Stephen L Gregory

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Targeting chromosomal instability in patients with cancer.Nature reviews. Clinical oncology · 2024
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Functional and regulatory aspects of oxidative stress response in X monosomy.In vitro cellular & developmental biology. Animal · 2021
    Article
  9. Review
  10. Basic and Translational Models of Cooperative Oncogenesis.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David L NewmanDepartment of Molecular and Biomedical Science, University of Adelaide, Adelaide 5006, Australia. david.newman@adelaide.edu.au.
Stephen L GregoryDepartment of Molecular and Biomedical Science, University of Adelaide, Adelaide 5006, Australia. stephen.gregory@flinders.edu.au.
University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations from the normal set of chromosomes are extremely common as cells progress toward tumourigenesis. Similarly, we expect to see disruption of normal cellular metabolism, particularly in the use of glucose. In this review, we discuss the connections between these two processes: how chromosomal aberrations lead to metabolic disruption, and vice versa. Both processes typically result in the production of elevated levels of reactive oxygen species, so we particularly focus on their role in mediating oncogenic changes.

Indexed as

AneuploidyGlycolysisOxidative StressAnimalsCarcinogenesisChromosome AberrationsDNA DamageHumansNeoplasmsReactive Oxygen SpeciesReactive Oxygen SpeciesaneuploidyDNA damageglycolysismetabolismoxidative stressreactive oxygen species

Identifiers

PMID31540349
PMCPMC6770258
OpenAlexW2973932969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.