Evidence map›Paper›PMID 31540344›Full record

ArticleInternational journal of molecular sciences2019

Proteomic Analysis in Morquio A Cells Treated with Immobilized Enzymatic Replacement Therapy on Nanostructured Lipid Systems.

J Víctor Álvarez, Susana B Bravo, María García-Vence, María J De Castro, Asteria Luzardo, Cristóbal Colón, Shunji Tomatsu, Francisco J Otero-Espinar, María L Couce

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Mucopolysaccharidosis IVA: Current Disease Models and Drawbacks.International journal of molecular sciences · 2023
    Review
  5. Review
  6. Proteomics in Inherited Metabolic Disorders.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Article
  9. Plasma Proteomic Analysis in Morquio A Disease.International journal of molecular sciences · 2021
    Article
  10. Article
  11. Review
  12. Mucopolysaccharidosis IVA: Diagnosis, Treatment, and Management.International journal of molecular sciences · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

J Víctor ÁlvarezDepartment of Pharmacology, Pharmacy and Pharmaceutical Technology, School of Pharmacy, Campus Vida, University of Santiago de Compostela, 15872 Santiago de Compostela, Spain. josevictor.Alvarezgonzalez@nemours.org.
Susana B BravoProteomic Platform, Health Research Institute of Santiago de Compostela (IDIS), Hospital Clínico Universitario de Santiago de Compostela, 15706 Santiago de Compostea, Spain. sbbravo@gmail.com.ORCID 0000-0001-7615-3079
María García-VenceProteomic Platform, Health Research Institute of Santiago de Compostela (IDIS), Hospital Clínico Universitario de Santiago de Compostela, 15706 Santiago de Compostea, Spain. mariagarve@outlook.es.
María J De CastroDepartment of Forensic Sciences, Pathology, Gynecology and Obstetrics, Pediatrics, Neonatology Service, Department of Paediatrics, Hospital Clínico Universitario de Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), CIBERER, MetabERN, 15706 Santiago de Compostela, Spain. mj.decastrol@gmail.com.
Asteria LuzardoDepartment of Pharmacology, Pharmacy and Pharmaceutical Technology, School of Sciences, Campus de Lugo, University of Santiago de Compostela, 27002 Lugo, Spain. asteriam.luzardo@usc.es.ORCID 0000-0002-8842-0960
Cristóbal ColónDepartment of Forensic Sciences, Pathology, Gynecology and Obstetrics, Pediatrics, Neonatology Service, Department of Paediatrics, Hospital Clínico Universitario de Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), CIBERER, MetabERN, 15706 Santiago de Compostela, Spain. cristobal.colon.mejeras@sergas.es.
Shunji TomatsuSkeletal Dysplasia Lab Nemours Biomedical Research Nemours/Alfred I. duPont Hospital for Children, 1600 Rockland Road, Wilmington, DE 19803, USA. shunji.tomatsu@nemours.org.
Francisco J Otero-EspinarDepartment of Pharmacology, Pharmacy and Pharmaceutical Technology, School of Pharmacy, Campus Vida, University of Santiago de Compostela, 15872 Santiago de Compostela, Spain. francisco.otero@usc.es.ORCID 0000-0001-9030-2253
María L CouceDepartment of Forensic Sciences, Pathology, Gynecology and Obstetrics, Pediatrics, Neonatology Service, Department of Paediatrics, Hospital Clínico Universitario de Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), CIBERER, MetabERN, 15706 Santiago de Compostela, Spain. mariluz.couce@usc.es.ORCID 0000-0003-4861-9905
Alfred I. duPont Hospital for Children · USInstituto de Investigación Sanitaria de Santiago · ESUniversidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Morquio A syndrome, or mucopolysaccharidosis type IVA (MPS IVA), is a lysosomal storage disease due to mutations in the N-acetylgalactosamine-6-sulfatase (

Indexed as

Drug Delivery SystemsAdultCells, CulturedChondroitinsulfatasesEnzyme Replacement TherapyFemaleHumansLipidsLiposomesMaleMucopolysaccharidosis IVNanostructuresProteomicsYoung AdultChondroitinsulfatasesGALNS protein, humanLipidsLiposomesenzyme replacement therapylysosomal disordersnanoparticlesproteomics

Identifiers

PMID31540344
PMCPMC6769449
OpenAlexW2974712087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.