Evidence map›Paper›PMID 31540342›Full record

ReviewJournal of clinical medicine2019

A Systematic Review and Meta-Analysis of the Accuracy of in VivoReflectance Confocal Microscopy for the Diagnosis of Primary Basal Cell Carcinoma.

Mihai Lupu, Iris Maria Popa, Vlad Mihai Voiculescu, Ana Caruntu, Constantin Caruntu

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  15. Recent Advances in Oral Squamous Cell Carcinoma.Journal of clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mihai LupuDepartment of Dermatology, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania. lupu.g.mihai@gmail.com.
Iris Maria PopaDepartment of Plastic and Reconstructive Surgery, "Bagdasar-Arseni" Clinical Emergency Hospital, 041915 Bucharest, Romania. irismpopa@gmail.com.
Vlad Mihai VoiculescuDepartment of Dermatology, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania. voiculescuvlad@yahoo.com.
Ana CaruntuDepartment of Oral and Maxillofacial Surgery, "Carol Davila" Central Military Emergency Hospital, 010825 Bucharest, Romania. ana.caruntu@gmail.com.
Constantin CaruntuDepartment of Dermatology, "Prof. N. Paulescu" National Institute of Diabetes, Nutrition and Metabolic Diseases, 011233 Bucharest, Romania. costin.caruntu@gmail.com.
Carol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · ROTitu Maiorescu University · RO

Funding

Ministerul Cercetarii si Inovarii 61PCCDI⁄2018 PN-III-P1-1.2-PCCDI-2017-0341
6 · The paper itself

Abstract

Basal cell carcinoma (BCC) is the most common cancer worldwide and its incidence is constantly rising. Early diagnosis and treatment can significantly reduce patient morbidity and healthcare costs. The value of reflectance confocal microscopy (RCM) in non-melanoma skin cancer diagnosis is still under debate. This systematic review and meta-analysis were conducted to assess the diagnostic accuracy of RCM in primary BCC. PubMed, Google Scholar, Scopus, and Web of Science databases were searched up to July 05, 2019, to collect articles concerning primary BCC diagnosis through RCM. The studies' methodological quality was assessed by the QUADAS-2 tool. The meta-analysis was conducted using Stata 13.0, RevMan 5.0, and MetaDisc 1.4 software. We included 15 studies totaling a number of 4163 lesions. The pooled sensitivity and specificity were 0.92 (95% CI, 0.87-0.95; I

Indexed as

basal cell carcinomadiagnostic test accuracyin vivometa-analysisreflectance confocal microscopysystematic review

Identifiers

PMID31540342
PMCPMC6780971
OpenAlexW2972726143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.