Evidence map›Paper›PMID 31540271›Full record

ArticleMolecules (Basel, Switzerland)2019

Selective Cannabinoid 2 Receptor Agonists as Potential Therapeutic Drugs for the Treatment of Endotoxin-Induced Uveitis.

Richard Frederick Porter, Anna-Maria Szczesniak, James Thomas Toguri, Simon Gebremeskel, Brent Johnston, Christian Lehmann, Jürgen Fingerle, Benno Rothenhäusler, Camille Perret, Mark Rogers-Evans and 6 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Orally bioavailable CBResearch square · 2026
    Article
  2. Genetically Encoded CBInternational journal of molecular sciences · 2026
    Article
  3. Chemical Probes for Investigating the Endocannabinoid System.Current topics in behavioral neurosciences · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. The Impact of the CBMolecules (Basel, Switzerland) · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. First In Class (Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Richard Frederick PorterDepartment of Pharmacology, Dalhousie University, Halifax, NS B3H 4R2, Canada. richard.porter@dal.ca.ORCID 0000-0002-1738-8705
Anna-Maria SzczesniakDepartment of Pharmacology, Dalhousie University, Halifax, NS B3H 4R2, Canada. Anna.Maria.Szczesniak@dal.ca.
James Thomas ToguriDepartment of Pharmacology, Dalhousie University, Halifax, NS B3H 4R2, Canada. ttoguri@dal.ca.
Simon GebremeskelDepartment of Microbiology and Immunology, Dalhousie University, Halifax, NS B3H 4R2, Canada. rassimon@gmail.com.
Brent JohnstonDepartment of Microbiology and Immunology, Dalhousie University, Halifax, NS B3H 4R2, Canada. brent.johnston@dal.ca.ORCID 0000-0001-5456-2824
Christian LehmannDepartment of Pharmacology, Dalhousie University, Halifax, NS B3H 4R2, Canada. chlehmann@dal.ca.ORCID 0000-0001-6419-9168
Jürgen FingerleRoche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland. juergen.fingerle@roche.com.
Benno RothenhäuslerRoche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland. benno.rothenhaeusler@roche.com.
Camille PerretRoche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland. camille.perret@roche.com.
Mark Rogers-EvansRoche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland. mark.rogers-evans@roche.com.
Atsushi KimbaraRoche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland. atsushi.kimbara@roche.com.
Matthias NettekovenRoche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland. matthias.nettekoven@roche.com.
Wolfgang GubaRoche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland. wolfgang.guba@roche.com.
Uwe GretherRoche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland. uwe.grether@roche.com.
Christoph UllmerRoche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland. christoph.ullmer@roche.com.ORCID 0000-0002-1044-6722
Melanie E M KellyDepartment of Pharmacology, Dalhousie University, Halifax, NS B3H 4R2, Canada. melanie.kelly@dal.ca.
Roche (Switzerland) · CHDalhousie University · CA

Funding

CIHR MOP-97768
6 · The paper itself

Abstract

(1) Background: The cannabinoid 2 receptor (CB

Indexed as

AnimalsAnti-Inflammatory AgentsCannabinoid Receptor AgonistsCell AdhesionCells, CulturedDisease Models, AnimalEndotoxinsLeukocytesMaleMiceMice, KnockoutModels, MolecularMolecular Docking SimulationMolecular StructureNeutrophilsReceptor, Cannabinoid, CB2Anti-Inflammatory AgentsCannabinoid Receptor AgonistsEndotoxinsReceptor, Cannabinoid, CB2anti-inflammatorycannabinoid 2 receptorselective cannabinoid ligandsstructure-activity relationshipsynthetic cannabinoidsuveitis

Identifiers

PMID31540271
PMCPMC6767236
OpenAlexW2972745012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.